Search for dissertations about: "breast cancer stem cells"
Showing result 1 - 5 of 42 swedish dissertations containing the words breast cancer stem cells.
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1. Stem and progenitor cells in brain ad breast malignancies
Abstract : Stem cells have qualities that clearly distinguish them from all other cells. Capabilities like self-renewal, differentiation and migration make them truly powerful. This thesis deals with different aspects of stem/progenitor cells in relation to cancer. READ MORE
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2. Patient-derived scaffolds as a 3D model for breast cancer
Abstract : Breast cancer is the most common cancer form in women worldwide. Many patients will have recurrent disease and more efficient targeted therapies are needed. The tumor microenvironment is a heterogenous complex mix of cells and components influencing critical cancer processes including progression, signaling and invasion. READ MORE
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3. Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA
Abstract : Breast cancer is a very heterogeneous disease in terms of clinical characteristics, genetic aberrations and prognosis. In Paper I, we focused on the CD44 molecule that often is aberrantly expressed in breast cancer and is widely used as a marker for cancer stem cells. READ MORE
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4. The breast cancer microenvironment and cancer cell secretion - specific effects on cancer progression and subtypes of cancer cells
Abstract : Breast cancer is the cancer form responsible for the most cancer-related deaths among women worldwide, and novel targeted therapies are highly needed. The tumor microenvironment consists of several components, including different cell types, extracellular matrix, oxygen and nutrient gradients and soluble factors that plays a key role in cancer progression. READ MORE
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5. The impact of the progranulin-sortilin axis on breast cancer stem cell activity and patient outcome
Abstract : Breast cancer is the most common cancer in women worldwide. Still today, despite current breast cancer therapies, many patients experience treatment resistance and relapse, which are believed to be due to failure in targeting treatment-resistant cancer stem cells. READ MORE