Search for dissertations about: "bronchial biopsies"

Showing result 1 - 5 of 20 swedish dissertations containing the words bronchial biopsies.

  1. 1. Airway inflammation in "healthy" smokers. Relation to lung function and high resolution CT findings

    Author : Ann Ekberg-Jansson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; smoking; bronchoalveolar lavage; bronchial biopsies; cytokines; lymphocytes; computed tomography; lung function; respiratory symptoms;

    Abstract : The aim of the present study was to characterize the inflammatory pattern in "healthy"smokers and relate it to lung function, high resolution computed tomography (HRCT) findings and respiratory symptoms in order to identify smokers at risk to develop COPD. Subjects were recruited from a population study "Men born 1933 in Göteborg". READ MORE

  2. 2. Immunopathological and Structural Alterations in Difficult to Control Asthma

    Author : Anders Bergqvist; Luftvägsinflammation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe asthma; bronchial thermoplasty; airway smooth muscle; neuroendocrine cells; inflammation; immune cells; remodelling;

    Abstract : Asthma is a chronic respiratory disorder affecting an estimated 300 million people worldwide. Most patients with asthma can be controlled with bronchodilators and low to moderate dose inhaled corticosteroids. However, an estimated 5-10% of the population presents a more troublesome disease, often referred to as severe asthma. READ MORE

  3. 3. Airway effects of diesel exhaust in healthy and asthmatic subjects

    Author : Charlotta Nordenhäll; Thomas Sandström; Ellinor Ädelroth; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; diesel exhaust; airway responsiveness; airway inflammation; lung function; asthmatics; immunohistochemistry; bronchial epithelium;

    Abstract : Several epidemiological studies have revealed an association between particulate matter (PM) pollution and various health effects. Importantly, there is evidence to suggest that individuals with pre-existing respiratory disease, such as asthma, are more sensitive to elevated ground levels of particulate matter as compared to healthy subjects. READ MORE

  4. 4. The relationship between inflammation and structural changes in the airways of the lower and upper respiratory tract : Studies in patients with asthma, Sjögren's syndrome, rhinitis and children with otitis media with effusion

    Author : Kawa Amin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; bronchial hyperresponsiveness; inflammatory cells; asthma; rhinitis; Sjögren s syndrome; children with otitis media with effusion; immunohistochemistry; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : The pathophysiology of asthma, Sjögrens syndrome (SS), rhinitis, and otitis media with effusion (OME) in children has been extensively investigated in upper and lower respiratory tract, respectively, and shown to comprise structural changes in the airways and involvement of inflammatory cells. By comparing diseases that have bronchial hyperresponsivenses or mucosal inflammation as a common denominator, it may be possible to learn more about the mechanisms underlying inflammation in the upper and lower respiratory tract. READ MORE

  5. 5. T cells in chronic obstructive pulmonary disease

    Author : Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Abstract : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. READ MORE