Search for dissertations about: "butyrylcholinesterase"

Found 4 swedish dissertations containing the word butyrylcholinesterase.

  2. 1. Molecular changes of acetylcholinesterase and butyrylcholinesterase in Alzheimer patients during the natural couse of the disease and treatment with cholinesterase inhibitors : insight into neurochemical mechanisms affecting the progression of the disease

    Author : Taher Darreh-Shori; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer disease; acetylcholinesterase; butyrylcholinesterase; cholinesterase inhibitors;

    Abstract : Deficits in central cholinergic neurotransmission in the brain correlate with cognitive impairment in Alzheimer disease (AD) patients. This fact has resulted in the introduction of cholinesterase inhibitors (ChEls) e.g. READ MORE

  4. 2. Studies on the catalytic mechanism of butyrylcholinesterase and the development of a cholinesterase assay for clinical applications

    Author : Håkan Eriksson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This investigation is concerned with the kinetic behaviour of butyrylcholinesterase and the development of a simple, fast and reliable method for the determination of cholinesterases in whole blood.Steady state kinetic studies with selective inhibitors and with a number of substrates at several different conditions were used in an attempt to explain the observed substrate activation of horse serum butyrylcholinesterase. READ MORE

  5. 3. Development of a Bioelectronic Tongue -Applications for Wastewater Analysis

    Author : Eva Dock; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytisk kemi; screen-printed electrode; multivariate data analysis; wastewater; Analytical chemistry; electronic tongue; biosensor array; amperometric;

    Abstract : A bioelectronic tongue has been developed for applications in wastewater analysis. The development of a biosensor array with complex signal analysis started from the idea of using group-selective phenol biosensors (tyrosinase and horseradish peroxidase) with chemometric analysis for signal processing. READ MORE

  6. 4. Apolipoprotein E and cholinergic enzymes : the interface in dementia

    Author : Swetha Vijayaraghavan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main confirmed genetic risk factor for sporadic form of Alzheimer’s disease (AD) is apolipoprotein E (ApoE) ε4 allele (APOE4). ApoE protein aids in receptor ligand mediated transport, distribution and metabolism of fatty acids and cholesterol. READ MORE