Search for dissertations about: "c-Jun"

Showing result 1 - 5 of 69 swedish dissertations containing the word c-Jun.

  1. 1. JNK/c-Jun Signaling and Peripheral Nerve Regeneration

    University dissertation from Lund University, Dept. of Cell and Organism Biology

    Author : Charlotta Lindwall; Lund University.; Lunds universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; neuropsychology; Neurology; Djurfysiologi; Animal physiology; JNK; signal transduction; nerve regeneration;

    Abstract : The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. READ MORE

  2. 2. Studies on two transcription regulatory proteins : cellular C-jun and adenovirus E1A

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Kerstin Sollerbrant; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenovirus; EIA; EIB; transcription; CtBP; c-Jun; Gal4;

    Abstract : STUDIES ON TWO TRANSCRIPTION REGULATORY PROTEINS: CELLULAR C-JUN AND ADENOVIRUS ElA. KERSTIN SOLLERBRANT Departrnent of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, S-171 77 Stockholm, Sweden. Adenoviruses cause Iytic infections in a range of mammalian cells, but can in certain cases also transform the host cell. READ MORE

  3. 3. Cellular mechanisms of taxane therapy in castration resistant prostate cancer

    University dissertation from Division of urological research

    Author : Martina Tinzl; Lund University.; Lunds universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; chemotherapy; taxane; c-jun; androgen receptor; PSA;

    Abstract : Chemotherapy of castration resistant prostate cancer (CRPC) is based on taxane formulations worldwide. Only 30-50 % of patients respond to this therapy and the exact cellular mechanisms of taxane resistance in PC cells are not fully elucidated. There is convincing evidence that androgen receptor (AR) is affected by exposure to these compounds. READ MORE

  4. 4. Effects of ethanol on the expression of immediate-early genes in nerve cells

    University dissertation from Division of urological research

    Author : Wei-Qun Ding; Lund University.; Lunds universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroadaptation; the central nervous system; AP-1; junD; junB; c-jun; fosB; c-fos; neuroblastoma SH-SY5Y; ethanol; immediate-early genes; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : Immediate-early genes of the fos and jun families encode proteins that dimerize to form a complex of activator protein 1 and regulate the expression of a number of genes in the nervous system. Ethanol has previously been shown to induce alterations in expression of fos and jun genes in the brain. READ MORE

  5. 5. TRAF6 stimulates TGFβ-induced oncogenic signal transduction in cancer cells

    University dissertation from Umeå : Umeå University

    Author : Shyam Kumar Gudey; Umeå universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; c-Jun; invasion; non-Smad; Notch; NICD; oncogenesis; presenilin1; PKCζ; prostate cancer; p21; p38; p300; Snail1; TGFβ; TβRI; TACE; TRAF6; ubiquitination; TGFbeta signal transduction; patologi; Pathology;

    Abstract : Prostate cancer is one of the leading causes of cancer-related deaths in men worldwide, with 10,000 new cases/year diagnosed in Sweden. In this context, there is an urgent need to identify new biomarkers to detect prostate cancer at an initial stage for earlier treatment intervention. READ MORE