Search for dissertations about: "c-src kinase"

Found 3 swedish dissertations containing the words c-src kinase.

  2. 1. Intracellular components involved in parathyroid sensing of extracellular calcium

    Author : Isaac G. Onyango; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Parathyroid hormone; secretion; Src kinase; ERK; PI 3-kinase; PKC; extracellular calcium; parathyroid cell; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Abstract : Parathyroid glands are the primary regulator of extracellular calcium ([Ca2+]e). Ca2+ plays a key role in many fundamental biological processes and is also an essential structural component of the skeleton. The parathyroid chief cells detect small changes in [Ca2+]e and respond by altering the secretion of parathyroid hormone (PTH). READ MORE

  4. 2. Mechanisms of activation of the aryl hydrocarbon receptor by novel inducers of the CYP1A1 gene

    Author : Maria Backlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AhR; omeprazole; primaquine; CYP1A1; ligand-independent activation; ligandbinding domain; protein tyrosine kinase; c-src kinase;

    Abstract : The aryl hydrocarbon receptor (AhR) functions as a ligand-activated transcription factor that is responsible for the activation of several response genes, of which the best characterised is the CYP1A1 gene. The prototype high affinity ligand for the AhR is the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). READ MORE

  5. 3. Receptor-operated signaling pathways in normal and diabetic pancreatic islet cell function

    Author : Fan Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Loss of glucose-dependent insulin release is an early pathogenetic event in human type 2 diabetes. Impaired glucose-mediated insulin secretion from pancreatic islet β-cells leads to insulin deficiency and thus hyperglycemia. READ MORE