Search for dissertations about: "cDNA microarray data"
Showing result 1 - 5 of 17 swedish dissertations containing the words cDNA microarray data.
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1. Classification and Computational Methods in Gene Expression Data Analysis
Abstract : The technology of cDNA microarrays has given us the possibility to monitor the state of cells by measuring the activity of thousands of genes simultaneously. This high-throughput techniqe has in cancer research allowed exploratory studies of molecular mechanisms behind for example metastasis and response to therapy. READ MORE
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2. Empirical Bayes Methods for DNA Microarray Data
Abstract : cDNA microarrays is one of the first high-throughput gene expression technologies that has emerged within molecular biology for the purpose of functional genomics. cDNA microarrays compare the gene expression levels between cell samples, for thousands of genes simultaneously. READ MORE
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3. Mining the transcriptome - methods and applications
Abstract : Regulation of gene expression occupies a central role in the control of the flow of genetic information from genes to proteins. Regulatory events on multiple levels ensure that the majority of the genes are expressed under controlled circumstances to yield temporally controlled, cell and tissue-specific expression patterns. READ MORE
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4. Using Minisequencing Technology for Analysing Genetic Variation in DNA and RNA
Abstract : In this thesis, the four-color fluorescence tag-microarray minisequencing system pioneered by our group was further developed and applied for analysing genetic variation in human DNA and RNA. A SNP marker panel representing different chromosomal regions was established and used for identification of informative SNP markers for monitoring chimerism after stem cell transplantation (SCT). READ MORE
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5. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer
Abstract : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. READ MORE