Search for dissertations about: "cDNA selection"

Showing result 1 - 5 of 23 swedish dissertations containing the words cDNA selection.

  2. 1. Avian MHC: variation and selection in the wild

    Author : Helena Westerdahl; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; polymorphism; balancing selection; cDNA; avian malaria; great reed warbler; Djurekologi; bird; Animal ecology; immune defence; MHC class II; Major Histocompatibility Complex; MHC class I;

    Abstract : In vertebrates the Major Histocompatibility Complex (MHC) plays a central role in the specific immune defence against various pathogens. Compared with other coding genes the MHC genes exhibit an extremely high level of polymorphism that is maintained by balancing selection. READ MORE

  4. 2. The CD40 Receptor - Target,Tool and Technology

    Author : Peter Ellmark; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; SPIRE; mammalian; library; cDNA; selection; receptor revision; phage display; scFv; human; CD40; antibodies;

    Abstract : CD40 is a cell surface receptor of pivotal importance that is expressed on several of the cells in the immune system. It is critical for many important events, such as T cell dependent B cell activation, isotype switching, somatic mutation and generation of B cell memory. READ MORE

  5. 3. Evidence for adaptive variation at the genes coding for cytosolic phosphoglucose isomerase (PGIC) in Festuca ovina L

    Author : Yuan Li; Biodiversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 3-D protein structure; purifying selection; positive selection; cDNA sequences; local adaptation; alvar grasslands; Festuca ovina; Phosphoglucose isomerase; PgiC loci; SNPs; nucleotide polymorphism; horizontal gene transfer;

    Abstract : The gene (Pgi) encoding the enzyme phosphoglucose isomerase (PGI) which plays a central role in the main pathways of carbon metabolism has been shown to be of adaptive significance in a wide range of different species. Earlier studies of enzyme electromorph variation in the grass Festuca ovina suggest that variation in cytosolic PGI (PGIC) may be involved in the adaptive response of F. READ MORE

  6. 4. The MHC genes: variation and impact on life-history traits in house sparrwos

    Author : Maria Karlsson; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MHC-I; house sparrow; 454-amplicon sequencing; cDNA; functional clustering; trans-species evolution; nestling survival; mate-choice;

    Abstract : In birds the major histocompatibility complex (MHC) organization differs both among and within orders. Galliformes often have simple arrangements with few transcribed MHC genes whilst many songbirds (Passeriformes) have a complex arrangement with many MHC genes and also presence of pseudo-genes. READ MORE

  7. 5. Combinatorial protein engineering applied to enzyme catalysis and molecular recognition

    Author : Malin Eklund; KTH; []
    Keywords : phage display; selection; enzyme; affinity domains; crystal structure; affibody; lipase; protein engineering; protein A; assembly;

    Abstract : The recent development of methods for constructing andhandling large collections (libraries) of proteins, from whichvariants with desired traits can be isolated, hasrevolutionized the field of protein engineering. Key elementsof such methods are the various ways in which the genotypes(the genes) and the phenotypes (the encoded proteins) arephysically linked during the process. READ MORE