Search for dissertations about: "cDNA sequences"

Showing result 1 - 5 of 56 swedish dissertations containing the words cDNA sequences.

  1. 1. Computational approaches for in-depth analysis of cDNA sequence tags

    Author : Per Unneberg; Joakim Lundberg; Leif Andersson; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; cDNA; EST; gene expression; SNP; SAGE; polymorphism; Bioteknik; Bioengineering; Bioteknik;

    Abstract : Major recent improvements in biotechnology have led to an accelerated production of DNA sequences. The completion of the human genome sequence, along with the genomes of more than two hundred other species, has marked the arrival of the genome era. The ultimate goal is to understand the structure and function of genomes and their genes. READ MORE

  2. 2. Evidence for adaptive variation at the genes coding for cytosolic phosphoglucose isomerase (PGIC) in Festuca ovina L

    Author : Yuan Li; Biodiversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 3-D protein structure; purifying selection; positive selection; cDNA sequences; local adaptation; alvar grasslands; Festuca ovina; Phosphoglucose isomerase; PgiC loci; SNPs; nucleotide polymorphism; horizontal gene transfer;

    Abstract : The gene (Pgi) encoding the enzyme phosphoglucose isomerase (PGI) which plays a central role in the main pathways of carbon metabolism has been shown to be of adaptive significance in a wide range of different species. Earlier studies of enzyme electromorph variation in the grass Festuca ovina suggest that variation in cytosolic PGI (PGIC) may be involved in the adaptive response of F. READ MORE

  3. 3. Transcriptome Analyses of the Nematode-trapping Fungus Monacrosporium haptotylum

    Author : Margareta Tholander; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; Microbiology; bacteriology; virology; mycology; Pathogenic fungi; Nematophagous fungi; Nematodes; Biological control; cDNA microarray; Transcriptome analysis; Nematode-trapping fungi; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Nematode-trapping fungi are soil living organisms with the ability to infect and kill nematodes. These fungi have developed specialized infection structures, traps for the capture of nematodes. To be able to identify genes in nematode-trapping fungi that are involved in the infection of nematodes cDNA microarrays were constructed. READ MORE

  4. 4. Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects

    Author : Marie Karlsson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genomic organisation; baculovirus-insect cells; catalytic triad; alfa beta hydrolase fold; tissue distribution; cDNA sequence; lipolysis; adipocyte; monoglyceride lipase; hormone-sensitive lipase; chromosomal localisation; Clinical biology; Klinisk biologi;

    Abstract : Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. READ MORE

  5. 5. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer

    Author : Markus Heidenblad; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FISH; Clinical genetics; PCR; cDNA microarray; array-based CGH; expression profiling; genomic profiling; Pancreatic cancer; gene amplification; Klinisk genetik;

    Abstract : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. READ MORE