Search for dissertations about: "cGMP-PKG"

Found 2 swedish dissertations containing the word cGMP-PKG.

  2. 1. Genes and proteins controlled by cGMP-PKG during retinal degeneration

    Author : Jiaming Zhou; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinal degeneration; cell death; cGMP-PKG; organotypic explant culture; RNA sequencing; mass spectrometry;

    Abstract : prevalence was reported as 1:3000-4000 worldwide, making it the main reason for blindness in the working population in industrial countries. The mutations of over 70 genes have been related to this genetic disorder, and there is generally no effective treatment, except for gene therapy for the RPE65 mutations. READ MORE

  4. 2. Studies on aquaporin 4 : a molecular determinant of brain water homeostasis

    Author : Eli Gunnarson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A well controlled brain water homeostasis is of utmost importance for an appropriate control of neuronal activity. Astrocytes express the water channel aqauporin 4 (AQP4) and play a key role for the maintenance of brain water homeostasis. Brain edema is a result of perturbed water homeostasis and involves astrocyte swelling. READ MORE