Search for dissertations about: "cGMP-dependent protein kinase II"
Found 4 swedish dissertations containing the words cGMP-dependent protein kinase II.
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1. Screening for Candidate Brain Tumor Genes : Identifying Genes that Cooperate with Platelet-Derived Growth Factor in Glioma Development and Progression
Abstract : Malignant primary brain tumors, gliomas, often overexpress both platelet-derived growth factor (PDGF) ligands and receptors providing an autocrine and/or paracrine boost to tumor growth. Glioblastoma multiforme (GBM) is the most frequent glioma. Its aggressive and infiltrative growth renders it extremely difficult to treat. READ MORE
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2. Cyclic nucleotide signalling in Alzheimer's disease postmortem brain
Abstract : The aim of this study was to determine the nature and significance of altered guanylyl cyclase (GC) and adenylyl cyclase (AC) signalling in Alzheimer's disease (AD) postmortem brain. Paper I describes a study of particulate and soluble GC activities in postmortem temporal cortex from a series of AD and matched control subjects. READ MORE
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3. The potential role of retinal cGMP-interaction partners within the degeneration mechanism causing Retinitis Pigmentosa
Abstract : The eye disease Retinitis Pigmentosa (RP) represents a heterogeneous group of inherited retinal dystrophies, and it has been estimated that 1 in 3000 to 7000 people worldwide has the disease. The symptoms of RP are photoreceptor degeneration that leads to night blindness, followed by a decline in peripheral and central vision, and potential blindness. READ MORE
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4. The role of red blood cells in cardiac and endothelial dysfunction in cardiometabolic disease
Abstract : Background: Cardiometabolic disease, which includes the combination of cardiovascular disease, especially coronary artery disease and type 2 diabetes (T2D), is a major health problem and cause of mortality worldwide. ST-elevation myocardial infarction (STEMI) occurs when coronary arteries are occluded and is regarded as a life-threatening disorder. READ MORE