Search for dissertations about: "cGMP"

Showing result 16 - 20 of 57 swedish dissertations containing the word cGMP.

  2. 16. Cyclic nucleotide signalling in Alzheimer's disease postmortem brain

    Author : Willy Lokwa Bonkale; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this study was to determine the nature and significance of altered guanylyl cyclase (GC) and adenylyl cyclase (AC) signalling in Alzheimer's disease (AD) postmortem brain. Paper I describes a study of particulate and soluble GC activities in postmortem temporal cortex from a series of AD and matched control subjects. READ MORE

  4. 17. Macrophages, Nitric oxide synthases and Heme oxygenases: possible roles during peripheral nerve regeneration

    Author : Sofia Magnusson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; satellite cells; peripheral ganglia; cell signalling; nerve regeneration; heme oxygenase; Macrophages; nitric oxide synthase; Animal physiology; Djurfysiologi;

    Abstract : The purpose of this study was to investigate the suggestions that macrophages, and the systems generating nitric oxide (NO) and carbon monoxide (CO), i.e. nitric oxide synthases (NOS) and heme oxygenases (HO), could be important for peripheral nerve regeneration. READ MORE

  5. 18. Oxygen sensing in Caenorhabditis elegans

    Author : Lina Zhao; Changchun Chen; Simon Tuck; Helena Edlund; Marc Pilon; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; C. elegans; acute hypoxia; G-protein; mitochondrial ROS; neuropeptide; GPCR;

    Abstract : Sufficient supply of oxygen (O2) to tissue is essential for survival of aerobicanimals. In mammals, there are constant homeostatic regulation mechanisms that act on different time scales to maintain optimal O2 delivery to tissues. The ability to detect and respond to acute oxygen shortages is indispensable to aerobic life. READ MORE

  6. 19. Effects of nitric oxide on gastric acid secretion in human gastric mucosa : functional and morphological studies

    Author : Anna Berg; Gunnar Flemström; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Hydrochloric acid (HCI) is secreted in high amounts by parietal cells in the human gastric mucosa and the resulting low pH constitutes an important factor for creating a suitable environment for the digestion. The normal gastric mucosa is equipped with an arsenal of protective mechanisms against the extreme chemical environment which the gastric acid creates. READ MORE

  7. 20. Regulation of endothelial transport

    Author : Shu Ming Liu; Göran K. Hansson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : A major role of endothelial cells is to control the influx of solutes into tissues. The aim of the research presented in this thesis was to gain knowledge about the regulation of endothelial transport in relation to the structure of the endothelial cytoskeleton and to elucidate the possible mechanisms of regulation. READ MORE