Search for dissertations about: "calcium-independent"

Showing result 1 - 5 of 9 swedish dissertations containing the word calcium-independent.

  2. 1. A thermostable alkaline protease from a new alkaliphilic Nesterenkonia sp

    Author : Shahrzad Bakhtiar; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; substrate specificity; crystallization; Biotechnology; Bioteknik; DNA-DNA hybridisation; 16S rDNA analysis; phenotypic characterisation; circular dichroism; differential scanning calorimetry; Nesterenkonia abyssinica; stability; calcium-independent; alkaline protease; alkaliphilic;

    Abstract : This thesis concerns a novel alkaline protease produced by an extremophilic microbial specie, designated as AL20, isolated from a feather sample collected at the shore of the alkaline soda lake Abjata in the Ethiopian Rift Valley. The isolate is a heterotrophic, alkaliphilic, halotolerant gram-positive, strictly aerobic, non-motile, non-spore forming bacterium. READ MORE

  4. 2. Formation and role of nitric oxide in host defense reactions in the urinary bladder

    Author : Edward R I Morcos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bladder cancer; BCG; cytokines; urinary tract infection; nitric oxide; nitric oxide synthase; nitrite; nitrate; capillary electrophoresis;

    Abstract : Nitric oxide (NO) is an important biological mediator and cell signaling molecule. It is also involved in several host defense reactions. NO is formed in vivo from L-arginine by the enzyme NO synthase (NOS). However, it can also be formed non-enzymatically from acidified nitrite. READ MORE

  5. 3. On the role of nitric oxide in bladder cancer and renal cell carcinoma

    Author : Olof T Jansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : urogenital tract; renal cell; transitional cell; carcinoma; nitric oxide; nitric oxide synthase; cytokines; apoptosis; BCG; cystitis;

    Abstract : The role of nitric oxide (NO) in tumour biology is unclear. There are conflicting reports in the literature whether NO will promote or inhibit tumour growth. The aim of the present thesis was to investigate the role of NO in bladder cancer and renal cell carcinoma. READ MORE

  6. 4. Studies on the structure, function and expression of phospholipase A2

    Author : Pontus Larsson Forsell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Phospholipase A2 (PLA2) enzymes are widely distributed and the enzymes possess different functions such as a role in digestion and inflammation. PLA2 catalyzes the hydrolysis of the sn-2 acylester bond of phospholipids, yielding a free fatty acid and a lysophospholipid. READ MORE

  7. 5. Molecular characterization and evolution of alpha-actinin : from protozoa to vertebrates

    Author : Ana Virel; Lars Backman; Kristina Djinovic-Carugo; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; alpha-actinin; evolution; spectrin repeat; intragene duplication; phylogenetic tree; spectrin superfamily; Biochemistry; Biokemi;

    Abstract : alpha-actinin is a ubiquitous protein found in most eukaryotic organisms. The ability to form dimers allows alpha-actinin to cross-link actin in different structures. In muscle cells alpha-actinin is found at the Z-disk of sarcomeres. READ MORE