Search for dissertations about: "calnexin"
Found 5 swedish dissertations containing the word calnexin.
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1. Calreticulins- Calcium-Binding Proteins with Functional Diversity and Evolutionary Duality
Abstract : Calreticulin is a multifunctional protein mainly localized in the endoplasmic reticulum in eukaryotic organisms, except yeasts. The protein comprises three distinct regions: the N-terminal N domain, the C-terminal C domain, and the central P domain, reflecting the functional diversity of calreticulin. READ MORE
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2. Folding and retention of rotavirus glycoproteins in the endoplasmic reticulum
Abstract : The endoplasmic reticulum (ER) is a membrane bound organelle composed of a network of cisternae stretching throughout the cytoplasm. Functionally, the ER performs many essential processes, such as glycosylation, and biosynthesis of lipids; it provides a redox potential condition for forming S-S linkages, and a quality control system, and functions as an intracellular calcium store. READ MORE
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3. Storage organelles that are distinct from the classical granules in human neutrophils
Abstract : The human neutrophil is a crucial participant in acute inflammation. Appropriate immune response is dependent on rapid direction of phagocytic cells through the tissue, towards the inflammatory focus. Such movement is governed by chemoattractants, e.g. READ MORE
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4. The quality control of MHC class I antigen presentation
Abstract : Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). READ MORE
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5. Characterisation of the novel endoplasmic reticulum chaperone ERDJ5
Abstract : Communication between cells depends to a large extent on interactions between secreted proteins and membrane receptors. Therefore their production and release must be strictly regulated. Proteins that are destined for the extracellular space assemble and fold in the endoplasmic reticulum (ER). READ MORE