Search for dissertations about: "cancer drug tests"

Showing result 1 - 5 of 10 swedish dissertations containing the words cancer drug tests.

  2. 1. Drug repositioning in chemoprevention of colorectal cancer

    Author : Naiqi Zhang; Allmänmedicin och klinisk epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug repositioning; Colorectal cancer CRC ; Pharmacoepidemiology; Chemoprevention; Melatonin; Proguanil; Atovaquone; Selective serotonin reuptake inhibitor SSRI ;

    Abstract : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. READ MORE

  4. 2. Aspects of Endocrine Therapy in Primary Breast Cancer. Risk Profiling and Adherence Perspectives for Improving Tailored Adjuvant Treatment

    Author : Christine Lundgren; LUCC: Lunds universitets cancercentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Abstract: Breast cancers are heterogeneous tumours. Prognostic markers are needed to better profile the patient´s risk, and predictive markers to indicate the expected benefit of systemic treatment. Using gene expression analyses, breast tumours can be divided into intrinsic subtypes. READ MORE

  5. 3. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer

    Author : Bo Hultman; Haile Mahteme; Bruno Walther; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastric cancer; peritoneal metastases; peritoneal carcinomatosis; epidemiology; prognostic factor; survival; neoadjuvant chemotherapy; cytoreductive surgery; HIPEC; health economy; costs; systemic chemotherapy; cultured tumor cells; fluorometric analysis; cancer drug tests; chemo-sensitivity; anti tumor drugs.; Surgery; Kirurgi;

    Abstract : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. READ MORE

  6. 4. Computer-aided drug design approaches in developing anti-cancer inhibitors

    Author : Chunxia Gao; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry;

    Abstract : The thesis entitled “computer-aided drug design approaches in developing anti-cancer drug” is divided into a total of six chapters. In the first chapter, an overview of drug discovery and development are introduced. READ MORE

  7. 5. Prostate cancer : investigating diagnosis, treatment and outcomes

    Author : Axel Möller; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Prostate cancer is difficult to study. The prostate is located so that it is hard to palpate and because of the dense pelvic bones it is hard to visualize using radiology such as computed tomography. The prostate increases in size with age and it can be irregular in shape and consistency without the presence of cancer. READ MORE