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Showing result 1 - 5 of 136 swedish dissertations matching the above criteria.

  1. 1. Cancer Risk Assessment of Glycidol Evaluation of a Multiplicative Risk Model for Genotoxic Compounds

    University dissertation from Stockholm : Department of Environmental Science and Analytical Chemistry, Stockholm University

    Author : Jenny Aasa; Stockholms universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; glycidol; 3-monochloropropane-1; 2-diol 3-MCPD ; genotoxicity; mutations; micronuclei; hemoglobin adducts; in vivo dose; multiplicative risk model; cancer risk assessment; human cancer risk; Environmental Chemistry; miljökemi;

    Abstract : Humans are exposed to chemical compounds in everyday life, both from the environment and from endogenous processes. Some compounds constitute a risk for cancer development. One such compound is glycidol, which is genotoxic and an animal carcinogen. It is the model compound of this work, partly due to its presence in food. READ MORE

  2. 2. Thyroid cancer studies on etiology and prognosis

    University dissertation from Umeå : Umeå universitet

    Author : Arne Hallquist; Umeå universitet.; [1994]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thyroid cancer; prognostic factors; etiology; occupation; medical ionizing radiation; reproductive; and family factors;

    Abstract : Thyroid cancer constitutes about 1% of all malignant tumours and the incidence is increasing in Sweden. It is rare in children before the age of 10. During puberty the female to male ratio increases to be two to three times more common in females. The ratio remains constant until menopause and thereafter declines. READ MORE

  3. 3. High-risk breast cancer: From biology to personalized therapeutic strategies

    University dissertation from Umeå : Umeå universitet

    Author : Toshima Z Parris; Göteborgs universitet.; Gothenburg University.; Göteborgs universitet.; Gothenburg University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; outcome prediction; molecular biomarker; 8p11-p12 amplification;

    Abstract : Adjuvant treatment regimens for breast cancer are primarily based on patient- and tumor-related factors, e.g. patient menopausal status, tumor stage and histological grade, and the status of molecular tumor markers (HER2/neu and the estrogen receptor). READ MORE

  4. 4. Image analysis of prostate cancer tissue biomarkers

    University dissertation from Division of Urological Cancers

    Author : Giuseppe Lippolis; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; image analysis; Time Resolved Fluorescence; automated Gleason; PSA; AR; fusion gene; TMAs;

    Abstract : Popular Abstract in English Prostate cancer is one of the most common cancers in the world and the second most common in men. The western world has the highest incidence rates. The causes of prostate cancer are not yet clear, however a number of risk factors have been identified such as familial history, ethnicity, diet and genetic events. READ MORE

  5. 5. Tumour evolution and novel biomarkers in breast cancer

    University dissertation from Division of Urological Cancers

    Author : Jana Biermann; Göteborgs universitet.; Gothenburg University.; Göteborgs universitet.; Gothenburg University.; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; gene signature; molecular biomarkers; tumour clonality; genomic instability; Swedish haemangioma cohort;

    Abstract : Several gene signatures have been proposed in the past two decades to improve outcome prediction for breast cancer patients and to guide treatment decisions. Current treatment guidelines, however, primarily focus on established clinicopathological features. READ MORE