Search for dissertations about: "candidate genes of diabetic nephropathy"

Showing result 1 - 5 of 6 swedish dissertations containing the words candidate genes of diabetic nephropathy.

  1. 1. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet

    Author : Anna Möllsten; Gisela Dahlquist; Lise Tarnow; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; Kidney diseases; Njursjukdomar;

    Abstract : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). READ MORE

  2. 2. Candidate Genes for Late Diabetic Complications

    Author : Eero Lindholm; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF; sekretion; LTA; Endocrinology; nephropathy; diabetes mellitus; retinopathy; neuropathy; genetic; UCP; diabetologi; AGER; MHc2TA; HLA-DQB1; Endokrinologi; secreting systems; diabetology;

    Abstract : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. READ MORE

  3. 3. Identification of the susceptibility genes in type 1 diabetes and diabetic nephropathy

    Author : Jun Ma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Type 1 Diabetes; Diabetic Nephropathy; Genetic Association; Single Nucleotide Polymorphism;

    Abstract : Genetic susceptibility plays an important role in the pathogenesis of type 1 diabetes (T1D) and diabetic nephropathy (DN). The present study aims to investigate the association between single nucleotide polymorphisms (SNPs) in candidate genes and DN. READ MORE

  4. 4. Genetic and functional analyses of diabetic nephropathy with focus on chromosome 3q

    Author : Dongying Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Diabetic nephropathy; chromosome 3; single nucleotide polymorphism; genetic association; gene expression;

    Abstract : Diabetic nephropathy (DN) is a complex disease affected by both genetic and environmental factors. Genetic and functional analyses of the susceptibility and/or resistance genes in DN may provide useful information for better understanding the pathogenesis and further developing novel therapeutic approaches in this disease. READ MORE

  5. 5. Searching for new biomarkers of diabetic nephropathy in Malaysian subjects with type 2 diabetes

    Author : Norhashimah Abu Seman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : According to the latest National Health and Morbidity Survey reports in year 2011, the prevalence of type 2 diabetes (T2D) in Malaysia has risen to 20.8%, much faster than expected. Of concern, 57% of T2D patients in Malaysia had diabetic nephropathy (DN). READ MORE