Search for dissertations about: "carbodiimide"

Showing result 1 - 5 of 12 swedish dissertations containing the word carbodiimide.

  1. 1. Chemical Derivatization in Combination with Liquid Chromatography Tandem Mass Spectrometry for Detection and Structural Investigation of Glucuronides

    Author : Matilda Lampinen Salomonsson; Mikael Hedeland; Ulf Bondesson; Calle Nilsson; Uppsala universitet; []
    Keywords : Pharmaceutical chemistry; Derivatization; mass spectrometry; glucuronide; drug metabolism; increased sensitivity; structural investigation; 2-chloro-1-methylpyridinium iodide CMPI ; 1-ethyl-3- 3-dimethylaminopropyl -carbodiimide EDC ; 2-picolylamine PA ; 1; 2-dimethylimidazole-4-sulfonyl chloride DMISC ; Farmaceutisk kemi;

    Abstract : This thesis presents novel approaches for structural investigation of glucuronides using chemical derivatization in combination with liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MSn).Today, LC-ESI-MSn is the dominant technique for quantitative as well as qualitative analyses of metabolites, due to its high sensitivity and selectivity. READ MORE

  2. 2. Multi-functional Hyaluronan Based Biomaterials for Biomedical Applications

    Author : Xia Yang; Dmitri Ossipov; Matthias Lutolf; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; biomaterials functionalizations; biomedical applications; orthogonal chemistry; drug delivery; tissue regeneration; MRI; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Abstract : This thesis presents strategies for constructing multi-functional biomaterials based on hyaluronan (HA) derivatives for various biomedical applications, such as drug delivery, tissue regeneration, and imaging biomaterials. The aim of this study is to improve the functionalities of HA biomaterials as well as simplify the preparation procedures. READ MORE

  3. 3. Poly (3-hydroxybutyrate) from a moderate halophile: production and modification for new applications

    Author : Marlene Munoz; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biopolymers; polyhydroxyalkanoates; polyhydroxybutyrate; moderate halophile; Halomonas boliviensis; fermentation; recovery; thermally induced phase separation; scaffolds; covalent modification; hydrophobic ion pairing; polyethylenemine; lysozyme.;

    Abstract : Polyhydroxybutyrate (PHB) is a homopolymer belonging to the family of biopolyesters, polyhydroxyalkanoates (PHA) produced by different bacteria and archaea as intracellular granules often under conditions of metabolic stress due to a limited supply of essential nutrients. The properties of the PHAs are similar to those of polyethylene and polypropylene and can hence replace these fossil based polymers in a large variety of applications. READ MORE

  4. 4. Functional Dendritic Materials using Click Chemistry : Synthesis, Characterizations and Applications

    Author : Per Antoni; Anders Hult; Michael Malkoch; Stefan Hecht; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dendrimer; Dendron; Dendritic; Hyperbranched; Click; Chemistry; CuAAc; One-Pot; Multi-functional; Simultaneous; Honeycomb; Isoporous; MALDI; NMR; GPC; TGA; DSC; Polymer chemistry; Polymerkemi;

    Abstract : Förfrågan efter nya och mer avancerade applikationer är en pågående process vilket leder till en konstant utveckling av nya material. För att förstå relationen mellan en applikations egenskaper och dess sammansättning krävs full förståelse och kontroll över materialets uppbyggnad. READ MORE

  5. 5. Self Assembled Monolayers for Quartz Crystal Microbalance based Biosensing

    Author : Annica Myrskog; Bo Liedberg; Sofia Svedhem; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : The work in this thesis has been focused on developing surfaces for use in biosensor systems, especially for quartz crystal microbalances. The surfaces were prepared by adsorption of organosulfur molecules onto gold substrates, so called self assembled monolayers (SAMs). READ MORE