Search for dissertations about: "carbon-carbon bond formation"
Showing result 1 - 5 of 18 swedish dissertations containing the words carbon-carbon bond formation.
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1. New Reactions with Allyl- and Allenylboron Reagents : Transition-Metal-Catalyzed and Transition-Metal-Free Carbon-Carbon Bond Formation Processes
Abstract : Organoboron compounds have been widely used in carbon-carbon bond formation reactions in organic synthesis and catalysis. This thesis is focused on cross-coupling reactions of allyl-, allenylboronic acids and their ester derivatives via transition metal catalysis or transition-metal-free processes. READ MORE
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2. Carbon-Carbon Bond Formation via Radical Cyclization and Transition Metal Catalysis
Abstract : Free radical cyclization methodology has been used extensively in synthesis for manipulation of complex molecules such as alkaloids, terpenes, carbohydrates, peptides and nucleic acids. The methodology has emerged as a result of work by physical organic chemists who determined rate constants for the most common radical reactions used in organic synthesis. READ MORE
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3. Transition metal-catalysed isomerisation of allylic alcohols : Applications to C−C, C−F and C−Cl bond formation
Abstract : The focus of this thesis has been to develop selective and atom-economical methods for carbon-carbon and carbon-heteroatom bond formation, and to some extent improve on existing findings in this area. More specifically, methods for the catalytic generation of enolates from allylic alcohols and their in situ functionalisation with electrophilic reagents are described. READ MORE
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4. The synthesis of chiral bidentate (N,N), (N,P) and (N,O) ligands and their use in metal-mediated asymmetric carbon-carbon bond formation
Abstract : This thesis covers three projects based on the metal-mediated formation of new chiral centers in the prescence of chiral ligands. The first project, involving (N,N)- ligands, concerns the synthesis of some (C2-symmetric bis(aziridine) ligands and the use of these in the addition of organolithium reagents to N-aryl protected imines leading to enantioselectivities of up to 89%. READ MORE
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5. Samarium(II)-mediated Reactions in Organic Synthesis - Method Development and Mechanistic Investigation
Abstract : This thesis describes the development of methods using divalent samarium reagents in organic synthesis. The main focus is placed on functional group reductions, but reductive formation of carbon-carbon bonds has also been investigated. READ MORE
