Search for dissertations about: "carbonylation"

Showing result 26 - 30 of 39 swedish dissertations containing the word carbonylation.

  2. 26. Oxidative Damage in Fish Used as Biomarkers in Field and Laboratory Studies

    Author : Bethanie Carney Almroth; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fish; oxidative stress; antioxidant enzymes; glutathione; protein carbonyls; lipid peroxidation; biomarkers; pollution; aging;

    Abstract : Many toxic xenobiotics entering into the aquatic environment exert their effects through redox cycling. Oxidative stress, incorporating both antioxidant defences as well as oxidative damage, is a common effect in organisms exposed to xenobiotics in their environment. READ MORE

  4. 27. Method development for [11C]carbon monoxide radiochemistry

    Author : Mélodie Ferrat; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Positron emission tomography (PET) is a non-invasive molecular imaging technique that has found extensive utility in biomedical research and in drug development. A fundamental pre-requisite for PET is the tracer, which is a biologically relevant molecule, labeled with a short-lived radionuclide. READ MORE

  5. 28. New Methods for the Synthesis of Vicinal Stereocenters : Palladium-Catalyzed Domino Reactions and Asymmetric Transfer Hydrogenation

    Author : Brinton Seashore-Ludlow; Somfai Peter; Kevin Booker-Milburn; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; asymmetric synthesis; domino reactions; palladium-catalyzed reactions; oxindoles; amino alcohols;

    Abstract : In this thesis the synthesis of vicinal stereocenters is investigated in two distinct contexts, namely the construction of 3,3-disubstituted oxindoles and the synthesis of b-hydroxy-a-amino acids. Both scaffolds are prevalent in a range of natural products and biologically relevant compounds and, therefore, methods for their synthesis are of great import. READ MORE

  6. 29. Stereoselective Nucleophilic Additions to Aldehydes and Development of New Methodology in Organic Synthesis

    Author : Tessie Borg; Olof Ramström; Siméon Arseniyadis; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This thesis is divided into four separate parts with nucleophilic addition to aldehydes as the common feature in three of them.The first part deals with the investigation of the stereochemical induction and elucidation of the factors that dictate the p-facial selectivities in Mukaiyama aldol addition to a- and a,b-heteroatom substituted aldehydes. READ MORE

  7. 30. Advances and Applications of Antibody Arrays - Proteomic Profiling of Pancreatic Disease

    Author : Anna Sandström Gerdtsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; affinity proteomics; antibody microarray; pancreatic cancer; pancreatitis; biomarker; immunosignature;

    Abstract : Recombinant antibody microarrays have advanced into indispensable tools for large-scale, high-throughput multiplexed serum proteomics. This thesis, based upon five original papers, deals with the development of an in-house designed antibody microarray platform, and its applications for serum profiling of pancreatic disease. READ MORE