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Showing result 1 - 5 of 43 swedish dissertations matching the above criteria.

  2. 1. Regulatory tools for managing chemicals risk at the workplace

    Author : Qian Ding; Sven Ove Hansson; Maria Albin; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Occupational Diseases; Chemicals; Carcinogens; Risk Management; Regulatory Toxicology; Occupational Exposure Limits; Chemicals Legislations; Risk Assessment; Acceptable Risk;

    Abstract : This thesis focuses on exacerbating chemicals risk in workplaces under the background of rapid industrialization in developing countries. The overall aim is to investigate the development of regulatory tools which aim at minimizing the health risks from chemical substances in the workplace. READ MORE

  4. 2. Identification and origin of potential background carcinogens : endogenous isoprene and oxiranes, dietary acrylamide

    Author : Eden Tareke; Rafter Joseph; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; Miljökemi; Environmental Chemistry; miljökemi;

    Abstract : The primary aims of this thesis are to discover carcinogens in the general population by identification of products of reaction with hemoglobin (Hb adducts) in blood from humans without known exposure, and tracing the origin of the adducts. Chemicals and/or their metabolites forming Hb adducts mostly also react with DNA and may thus cause mutations, a key event in carcinogenesis. READ MORE

  5. 3. DNA adducts as biomarkers of exposure to some dietary carcinogens

    Author : Tina Jurén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Humans are exposed to many chemicals via intake of food and drink and there are strong associations between dietary factors and cancer. Exposure to the dietary carcinogens acrylamide and acetaldehyde are potential health risks that have made the headlines. High levels of acrylamide are found in various food items, such as potato chips. READ MORE

  6. 4. Monitoring and cancer risk assessment of carcinogens, particularly alkenes in urban air

    Author : Margareta Törnqvist; Stockholms universitet; []
    Keywords : ;

    Abstract : .... READ MORE

  7. 5. Studies on DNA adducts and carcinogenesis with 2-nitrofluorene as a model substance

    Author : Xian-Shu Cui; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 2-nitrofluorene; carcinogens; DNA adducts; preneoplastic lesion; tumor;

    Abstract : A number of carcinogens or their electrophilic intermediates are able to bind covalently to DNA, forming DNA adducts. DNA adducts may cause gene mutations if they are misrepaired or remain unrepaired before DNA replication occurs. DNA adduct formation is believed to be the initial step of chemical carcinogenesis. READ MORE