Search for dissertations about: "carcinogens"

Showing result 6 - 10 of 43 swedish dissertations containing the word carcinogens.

2. 6. Chromosome aberrations and environmental exposures in acute leukemia

   Author : Ragnhild Rosengren Lindquist; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acute leukemia; chromosome 3; chromosome 8; fragile site; occupational exposure; mutagen exposure; case-control study; trisomy; benzene; organic solvent; petroleum; epidemiology; environmental carcinogens; painter; driver;

   Abstract : The aims of this thesis are to evaluate the role of environmental exposures, especially professional exposure to organic solvents and petroleum products in the etiology of acute leukemia and to investigate if there is a correlation between the exposure to a specific leukemogen factor and a clonal chromosome aberration of the leukemic cells. Papers I and II present results of a case-control study of environmental exposures, in all occupations during life-time, medical treatments with medicines, chemotherapy and radiation, tobacco-use and the exposure to chemical compounds in private life in 120 patients with acute leukemia and of 120 controls, matched for age (+ 4 years), residence and sex. READ MORE

4. 7. Gender differences in chemical carcinogenesis

   Author : Sandeep Kadekar; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Gender differences in cancer incidence and mortality is a regular finding in epidemiological studies. In addition to reproductive organs this pattern is also seen in non-reproductive organs, with men being the most affected gender for the majority of cancer-sites. READ MORE

5. 8. Environmental Contaminants, Recombination and Cancer : Investigations on the molecular mechanisms of spontaneous and induced recombination in the hprt gene of Chinese hamster cells

   Author : Thomas Helleday; Mark Meuth; Stockholms universitet; []
   Keywords : toxikologisk genetik; Genetic Toxicology;

   Abstract : Recombination results in rearrangement of the genetic material contained in the chromosomes inherited from the mother and father and this process is also involved in repairing damage to the genome. Occasionally, the machinery that performs recombination malfunctions and this may lead to illegitimate recombination events which inactivate tumor suppressor genes or activate protooncogenes. READ MORE

6. 9. Aerosols of Isocyanates, Amines and Anhydrides : Sampling and Analysis

   Author : Jakob Dahlin; Gunnar Skarping; Robert P. Streicher; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; isocyanate; amine; aminoisocyanate; organic acid anhydride; denuder; impactor; impinger; air sampling; LC-MS; LC-CLND; di-n-butylamine; DBA; thermal degradation; aerosol; particles; TDI; MDI; HDI; ICA; MIC; IPDI; exposure; occupational health; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Abstract : This thesis presents methods for air sampling and determination of isocyanates, amines, aminoisocyanates and anhydrides. These organic compounds are generated during thermal degradation of polymers such as polyurethane (PUR) or epoxy.Isocyanates, amines and anhydrides are airway irritants known to cause occupational asthma. READ MORE

7. 10. Airborne Isocyanates, Aminoisocyanates and Amines

   Author : Daniel Karlsson; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental health; Miljökemi; Environmental chemistry; amines; aminoisocyanates; isocyanates; polyurethane; exposure; occupational; thermal degradation; chemiluminescence; mass spectrometry; Liquid chromatography; gas chromatography; Miljömedicin; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

   Abstract : Isocyanates are used in the production of polyurethane (PUR). Exposure to isocyanates is associated with respiratory disorders and may occur during production or processing of PUR. During thermal degradation of PUR, amines and aminoisocyanates are formed in addition to isocyanates. READ MORE