Search for dissertations about: "cardiac calcium"
Showing result 1 - 5 of 49 swedish dissertations containing the words cardiac calcium.
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1. Calcium channel activity and force regulation in smooth muscle: Effects of polyamines and growth stimulation
Abstract : The initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. READ MORE
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2. Novel and Traditional Risk Factors for Coronary Artery Disease : Role of Coronary Artery Calcium, Lipidomics, Psychosocial Factors and Diet
Abstract : Background: The aim of the research reported in this thesis was to determine the association of novel and traditional risk factors with coronary artery calcium (CAC), a marker of subclinical coronary artery disease (CAD) in healthy individuals. In addition, we investigated the effects of a vegetarian, compared to a meat diet, on novel and traditional risk factors in patients with diagnosed CAD. READ MORE
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3. Cardiac lipids and their role in the diseased heart
Abstract : Lipids play an essential role within the heart as they are involved in energy storage, membrane stability and signaling. Changes in cardiac lipid composition and utilization may thus have profound effects on cardiac function. Importantly, the diseased heart is associated with intracellular metabolic abnormalities, including accumulation of lipids. READ MORE
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4. Patient stratification and treatment effects in diseases with disturbed cardiac function
Abstract : Background: Cardiovascular disease characteristics are often measured using a combination of different measurement modalities. By combining information from these modalities using statistical modelling we can gain additional knowledge about these diseases. READ MORE
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5. Oxidative stress and calcium signalling : implications for diabetes and cardiac glycosides
Abstract : The signal transduction processes by which an individual cell is able to recognize and respond to its external environment are critical to determining its survival as well as that of the entire organism. In the current study we have investigated the intracellular signalling cascades activated downstream of two separate stimuli: the diabetic milieu and the cardiac glycoside, ouabain. READ MORE