Search for dissertations about: "cardiomyocytes"

Showing result 1 - 5 of 50 swedish dissertations containing the word cardiomyocytes.

  1. 1. Cardiomyocyte Cell Cycle, Renewal and Isolation

    University dissertation from Cardiovascular Laboratory, Center for Stem Cell Biology, Lund

    Author : Stuart Walsh; Lunds universitet.; Lund University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; binucleation; Cardiomyocytes; surface marker; troponin-T; mitosis; microarray; cell cycle; FACS;

    Abstract : Popular Abstract in Swedish Hjärtsjukdom som orsakas av skador på hjärtmuskelceller är en av de vanligaste dödsorsakerna världen över. En framtida önskvärd behandling vore att kunna stimulera kroppens egna förmåga att återskapa hjärtmuskelceller, eller att isolera hjärtmuskelceller framställda i cellkultur. READ MORE

  2. 2. In vitro toxicity testing using human pluripotent stem cell derivatives

    University dissertation from University of Gothenburg

    Author : Gustav Holmgren; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicity testing; human pluripotent stem cells; cardiomyocytes; hepatocytes; microarray; quantitative proteomics; bioinformatics; transcriptomics; microRNA; Medical sciences; Medicin;

    Abstract : .... READ MORE

  3. 3. About hyaluronan in the hypertrophic heart studies on coordinated regulation of extracellular matrix signalling

    University dissertation from Umeå : Umeå universitet

    Author : Urban Hellman; Umeå universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hyaluronan; hyaluronan synthases; gene expression; extracellular matrix; cardiac hypertrophy; rat wistar; male ; cardiomyocytes; growth factors; fibroblasts; microvesicles; exosomes; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. READ MORE

  4. 4. Cardiac hypertrophy transcription patterns, hypertrophicprogression and extracellular signalling

    University dissertation from Umeå : Umeå universitet

    Author : Nina Gennebäck; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac hypertrophy; HCM; gene expression; OPLS-DA; multivariate dataanalysis; cardiomyocytes; exosomes; microvesicles; medicin; Medicine;

    Abstract : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. READ MORE

  5. 5. Pathophysiological importance of Beta1-Adrenergic receptor autoantibodies in the development of cardiomyopathy and heart failure. Clinically and experimentally

    University dissertation from Umeå : Umeå universitet

    Author : Lisa Buvall; Göteborgs universitet.; Gothenburg University.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dilated Cardiomyopathy; Beta1 Adrenergic Receptor; Antibody; Cardiac; Function; Intravenous Immunoglobulin; Immunoadsorption; Cultured Cardiomyocytes; rat; mice; GRK2;

    Abstract : Idiopathic Dilated Cardiomyopathy (DCM) is a heart muscle disease of unknown originthat is characterized by ventricular dilation and the impaired contraction of the left orboth ventricles, resulting in progressive heart failure and sudden cardiac death. Antibodiesagainst different cardiac proteins have been found in DCM; they include antibodiesagainst the 1-adrenergic receptor (1AR). READ MORE