Search for dissertations about: "cartilage destruction"

Showing result 1 - 5 of 31 swedish dissertations containing the words cartilage destruction.

  1. 1. Cartilage destruction - Release of type IX collagen in joint disease

    University dissertation from Department of Experimental Medical Science, Lund Univeristy

    Author : Mikael Danfelter; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cartilage destruction; matrix metalloproteinase 13; ECM; assay; neoepitope; NC4 domain; Type IX collagen; fragment;

    Abstract : Cartilage is of vital importance for the function of joints. It is characterized by a prominent extracellular matrix (ECM) that is produced and maintained by relatively few cells of one type, the chondrocyte. READ MORE

  2. 2. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis

    University dissertation from Anette Bjärdahlen, BMC C13, 221 84 Lund, Sweden

    Author : Anette Bjärdahlen; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arthritis; collagen; cartilage; myofibroblasts; pannus; proteoglycan; Skeleton; muscle system; rheumatology locomotion; reumatologi; Skelett; muskelsystem;

    Abstract : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. READ MORE

  3. 3. The collagen fibrillar network: Sequential degradation of its constituents by tissue metalloproteinases

    University dissertation from Anette Bjärdahlen, BMC C13, 221 84 Lund, Sweden

    Author : Terrence Heathfield; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolism; Metabolism; Biochemistry; collagen; fibromodulin; cartilage; osteoarthritis; Biokemi;

    Abstract : The cartilage matrix is made up of a fibrillar meshwork comprising type II collagen and other associated proteins. One main function of this network is to retain the large aggregating proteoglycan, aggrecan, a vital component in the regulation of fluid flux in cartilage. READ MORE

  4. 4. Molecular and clinical studies of cartilage and bone macromolecules in arthritis

    University dissertation from Department of Rheumatology, Lund University

    Author : Bengt Månsson; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Prognosis; Tissue damage; Bone markers; Cartilage markers; Rheumatoid arthritis; Psoriatic arthritis; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

    Abstract : The pathogenesis of inflammatory arthritides include synovial inflammation and joint tissue destruction. Tissue destruction has traditionally been regarded a consequence of inflammation, but recent observations indicate that the processes are not always closely linked and may proceed uncoupled. READ MORE

  5. 5. Tissue destruction in arthritis : Experimental studies

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Esbjörn Larsson; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. READ MORE