Search for dissertations about: "cartilage remodelling"

Showing result 1 - 5 of 6 swedish dissertations containing the words cartilage remodelling.

  1. 1. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis

    Author : Anette Bjärdahlen; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arthritis; collagen; cartilage; myofibroblasts; pannus; proteoglycan; Skeleton; muscle system; rheumatology locomotion; reumatologi; Skelett; muskelsystem;

    Abstract : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. READ MORE

  2. 2. Hormone replacement therapy in rheumatoid arthritis

    Author : Helena Forsblad d'Elia; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; randomised controlled trials; hormone replacement therapy; estrogen; osteoporosis; bone mineral density; bone remodelling; cartilage remodelling; cytokines; insulin-like growth factor 1;

    Abstract : Rheumatoid arthritis (RA) is 2-3 times more frequent in women as compared to men. The peak incidence in women coincides with the years around the menopause and the course of RA is also influenced by events associated with hormonal alterations. READ MORE

  3. 3. Cartilage Oligomeric Matrix Protein (COMP). Functions in collagen binding and assembly

    Author : Krisztina Rosenberg; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; Klinisk biologi;

    Abstract : Connective tissues contain a prominent extracellular matrix that provides mechanical and physical properties. This extracellular matrix contains as a major constituent a network of collagen fibres. These are composed of collagen fibrils, which in turn are assembled from many collagen molecules aligned parallel to each other. Several proteins, e. READ MORE

  4. 4. Chondrocyte and extracellular matrix alterations in equine cartilage during development and inflammation

    Author : Maria Löfgren; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Osteoarthritis (OA) is a disease involving inflammation and subsequent degeneration of joint tissues. The disease progresses with time-dependent stages of degeneration, loss and remodelling of the extracellular matrix (ECM) of articular cartilage, and phenotypical changes in the chondrocytes. READ MORE

  5. 5. Survival of onlay bone grafts. A study in the adult rat

    Author : Monica Gordh; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; polytetrafluoroethylene; artificial; membrane; immunohistochemistry; cortical perforations; bone morphogenetic protein; bone marrow; bone; bone grafts; Odontologi; stomatology; Odontology; skull; tibia;

    Abstract : The aim of this thesis was to study onlay bone grafting in the adult rat to improve graft incorporation and perservation of graft size. In 167 adult isogeneic lewis rats, the size maintenance and bone formation at the graft-host interface of uni- and bicortical onlays positioned in various environments and treatments were investigated. READ MORE