Search for dissertations about: "caspase-1"
Showing result 1 - 5 of 30 swedish dissertations containing the word caspase-1.
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1. The role of caspase-1, caspase-4, NLRP3 and IL-1RA in bladder epithelial cells infected by uropathogenic Escherichia coli
Abstract : Urinary tract infection is one of the most common infections and is mostlycaused by uropathogenic Escherichia coli (UPEC). The inflammasomeassociatedproteins caspase-1, caspase-4 and NLRP3 are essential in the hostcell response during urinary tract infection by regulating IL-1β release. READ MORE
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2. Inflammatory cell death of human macrophages induced by Aggregatibacter actinomycetemcomitans leukotoxin
Abstract : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a bacterium mainly associated with aggressive forms of periodontitis. Among its virulence factors, a leukotoxin is suggested to play an important role in the pathogenicity. READ MORE
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3. Macrophage Activation and AP-1 in Atherosclerosis
Abstract : High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. READ MORE
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4. Staphylococcus aureus bacteremia, molecular epidemiology and host immune response
Abstract : Staphylococcus aureus is a major pathogen responsible for a considerable disease burden worldwide. It may cause a wide array of infections, from superficial skin infections to invasive bacteremia and complications such as infective endocarditis (IE) and osteomyelitis. This thesis aimed to investigate aspects of the molecular epidemiology of S. READ MORE
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5. On the role of innate cell interactions in inflammation and leukemia
Abstract : Inflammatory cells of the innate immune system launch rapid and powerful effector responses in the combat against infectious pathogens. However, these inflammatory mediators may cause excessive damage to the host and, therefore, require rigid control systems to maintain the delicate balance between prompt clearance of infections and the risk of developing immunopathology. READ MORE