Search for dissertations about: "catabolism dialysis"

Found 5 swedish dissertations containing the words catabolism dialysis.

  2. 1. Lipoprotein lipase in hemodialysis patients and healthy controls : effects of heparin

    Author : Birgit Näsström; Per-Ola Attman; Umeå universitet; []
    Keywords : dalteparin; dialysis; lipoprotein metabolism; LMWH; LPL; triglycerides; UFH; uremia; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

    Abstract : Mortality from cardiovascular disease in patients on chronic hemodialysis (HD) is 10 to 20 times greater than in the general population. One major risk factor is renal dyslipidemia, characterised by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. READ MORE

  4. 2. Lipoprotein lipase activity is reduced in dialysis patients. Studies on possible causal factors

    Author : Dana Mahmood; Bernd Stegmayr; Gunilla Olivecrona; Per Ola Attman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemodialysis; lipoprotein lipase; ANGPTL3; ANGPTL4; citrate dialysate; dialyzer.; medicin; Medicine;

    Abstract : Cardiovascular disease is a major cause of mortality and morbidity in patients on chronic haemodialysis (HD). One main contributing factor is renal dyslipidaemia, characterized by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. READ MORE

  5. 3. Erythrocyte amino acids in health and renal failure and their association to the IGF-I/IGFBP-1 axis

    Author : José Carolino Divino Filho; Karolinska Institutet; Karolinska Institutet; []
    Keywords : amino acid; ASP DNA; catabolism dialysis; erythrocytes; glutamate; glutamine; health; human; IGF-I; IGFBP-1; muscle; plasmaprotein intake; rat; renal failure; uraemia;

    Abstract : Abnormalities in amino acids (AA) metabolism in uraemia have mainly been reported to occur in plasma and muscle. No investigation has been undertaken to evaluate the AA levels in plasma, muscle and red blood cells (RBC) simultaneously, although the RBC pool of free AA constitutes a large proportion of the free AA in blood, and RBC are involved in the interorgan transport of AA. READ MORE

  6. 4. Regulation of insulin-like growth factor binding protein-1 (IGFBP-1) and implications in catabolic conditions

    Author : Björn Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis has studied the regulation of IGFBP-1 (insulin-like growth factor binding protein 1), which is one factor regulating the bioavailability of IGF-I with special interest how IGFBP-1 is regulated in vitro and in humans, especially in diabetes and catabolic conditions. The IGFBP-1 cDNA was cloned and used for studies in human hepatoma cells, HepG2, which showed that both insulin and IGF-I could decrease IGFBP-1 in the cell conditioned medium. READ MORE

  7. 5. The effects of haemodialysis and metabolic acidosis on protein metabolism

    Author : Erland Löfberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : haemodialysis; metabolic acidosis; skeletal muscle; protein metabolism; amino acids; branched-chain amino acids; flooding dose; ribosomes; glucocorticoids;

    Abstract : Chronic renal failure and uraemia are characterised by gradual loss of renal function with an accumulation of metabolic and toxic waste products as well as disturbances in several organs and hormone functions. Two factors affect the catabolism in renal failure - i.e., the haemodialysis procedure and metabolic acidosis. READ MORE