Search for dissertations about: "cathelicidin"

Showing result 1 - 5 of 26 swedish dissertations containing the word cathelicidin.

  1. 1. Studies of the pathogenesis of Shiga toxin-producing Escherichia coli-induced hemolytic uremic syndrome

    University dissertation from Paediatrics, Faculty of Medicine, Lund University

    Author : Ida Arvidsson; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; hemolytic uremic syndrome; Shiga toxin; complement; hemolysis; microvesicles; cathelicidin;

    Abstract : Hemolytic uremic syndrome (HUS) is characterized by non-immune hemolytic anemia, thrombocytopenia and acute kidney failure. The most common form of HUS is associated with gastrointestinal Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) infection. EHEC are non-invasive strains with Shiga toxin as the unique virulence factor. READ MORE

  2. 2. Functional dualism of antimicrobial host defence peptides

    University dissertation from Paediatrics, Faculty of Medicine, Lund University

    Author : Åse Björstad; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; apoptosis; cathelicidin; host defence peptide; interleukin 8; LL-37; permeabilisation;

    Abstract : Antimicrobial host defence peptides are central to innate immunity and many possess direct antimicrobial actions on bacteria as well as indirect immunomodulatory functions on human leukocytes. Different variants of the bifunctional Helicobacter pylori peptide, Hp(2-20), were synthesised and inhibition zone assays and chemiluminescence systems were employed for determination of direct antimicrobial action and superoxide release (immunomodulatory) from human neutrophils, respectively. READ MORE

  3. 3. Expression of cathelicidin antimicrobial peptides in man and rat

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Stefan Termén; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LL-37; rCRAMP; butyrate; colonic epithelium; central nervous system; transcription;

    Abstract : Endogenous antimicrobial peptides are effectors of innate immunity. They kill microorganisms by disrupting their cell membranes, but are also believed to have signaling functions in the immune system. They are present in epithelia, secretions and phagocytic cells. READ MORE

  4. 4. Studies of the role of the cathelicidin peptide LL-37 in epithelial biology

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Clara Ibel Chamorro Jimenez; Karolinska Institutet.; Karolinska Institutet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The biology of epithelial immunity as well as of tissue repair is complex and highly regulated. A variety of molecules, cell types, and biological processes such as, cell differentiation, proliferation and migration, programmed cell death and antimicrobial mechanisms contribute to maintaining a balance between tissue damage and tissue repair. READ MORE

  5. 5. Studies on Staphylococcus epidermidis biofilm formation and the bacterial interaction with the human cathelicidin antimicrobial peptide LL-37

    University dissertation from Stockholm : Karolinska Institutet, Dept of Women's and Children's Health

    Author : Eva Hell; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The long-term use of central venous catheters for delivering nutrients and drugs in preterm neonates has been related to nosocomial infections. The majority of late-onset sepsis in very preterm infants (... READ MORE