Search for dissertations about: "cathelicidin"

Showing result 21 - 25 of 28 swedish dissertations containing the word cathelicidin.

  2. 21. Eosinophilic dermatosis implications of skin-commensal bacteria and antimicrobial peptides and proteins at birth

    Author : Annika Nelson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : At birth, the newborn infant is transferred from a sterile life in utero to an earthly life in coexistence with microbes. This transition includes the potential danger of a microbial invasion through the epithelial linings, and the infant must find a balance between elimination of harmful pathogens and cooperation with microorganisms that are of benefit. READ MORE

  4. 22. Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis

    Author : Petra Neregård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability. Despite recent progress in the therapeutic field of RA, the exact molecular mechanisms responsible for chronic joint inflammation are not yet completely understood. READ MORE

  5. 23. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

    Author : Thorgerdur Sigurdardottir; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; LL-37; M1 protein; S. pyogenes; Toll-like receptors; phenylephrine; nitr1c oxide; antimicrobial peptides;

    Abstract : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. READ MORE

  6. 24. Antimicrobial peptides and proteins in host-microbe interaction and immediate defense

    Author : Ylva Kai-Larsen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antimicrobial peptides and proteins (AMPs) are effector molecules of innate immunity and are capable to kill a broad spectrum of microbes, i.e. bacteria, fungi and viruses. They are widespread in nature and have been found in almost all species of the animal kingdom, as well as in plants. READ MORE

  7. 25. Identification of novel inducers for LL-37 expression : assay development and mechanistic studies

    Author : Frank Nylén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The remaining reservoir of effective antibiotics is running out and more and more pathogens are gaining resistance, even to the last line of antibiotics. Therefore, novel treatment regimens against bacterial infections are urgently needed. READ MORE