Search for dissertations about: "cathepsin B"

Showing result 1 - 5 of 31 swedish dissertations containing the words cathepsin B.

2. 1. Amyloid β-protein, Cystatin C and Cathepsin B as Biomarkers of Alzheimer's Disease

   Author : Johan Sundelöf; Lars Lannfelt; Lena Kilander; Hans Basun; Johan Sundstrom; Laura Fratiglioni; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer´s disease; amyloid β-protein; cystatin C; cathepsin B; biomarkers; risk factors; epidemiology; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; Medicin; Medicine;

   Abstract : It is suggested that Alzheimer’s disease (AD) is caused by an imbalance between production, degradation and clearance of the amyloid-β (Aβ) protein. This imbalance leads to aggregation of Aβ and tau proteins and neurodegeneration in the brain. READ MORE

4. 2. Cystatin C in the Eye and in Specific Model Systems

   Author : Johan Wasselius; Lund Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; protein uptake; ciliary body; lens; cornea; retina; eye; Cystatin C; cathepsin B; Oftalmologi;

   Abstract : It is a necessity of life to make proteins, and it is an equal necessity to degrade those proteins, to eliminate dysfunctional proteins, and leave room for new ones. The processes of protein synthesis and degradation into peptides - proteolysis - have attracted a great interest during the last decades. READ MORE

5. 3. Cathepsin D released from lysosomes mediates apoptosis

   Author : Katarina Kågedal; Marja Jäättelä; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Last year (2002), the Nobel Prize in Physiology or Medicine was awarded to three scientists who have conducted pioneer research on programmed cell death. In the human body, more than a thousand billion cells are created every day, and an equal number die, thus programmed cell death, or apoptosis, is an important mechanism for maintaining tissue homeostasis and protecting against disease. READ MORE

6. 4. The role of Moraxella catarrhalis outer membrane proteins in pathogenesis

   Author : Taras Manolov; Malmö Klinisk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cathepsin G; inflammation; serum resistance; C3; complement; Moraxella catarrhalis; antichymotrypsin; affinity chromatography; purification;

   Abstract : Moraxella catarrhalis is an important respiratory pathogen. It is a common cause of otitis media in children, a usual infections agent in sinusitis and makes up to 10% of all exacerbations of chronic obstructive pulmonary disease (COPD). READ MORE

7. 5. Acute Pancreatitis. Studies on smoking and protease activation

   Author : Björn Lindkvist; Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen; Acute pancreatitis; trypsinogen activation peptide cathepsin B; incidence; smoking; nicotine; traumatologi; ortopedi; Kirurgi; traumatology; Surgery; orthopaedics; Gastroenterologi; Public health; epidemiology; Folkhälsa; epidemiologi; Gastro-enterology;

   Abstract : Background and aims: Activation of pancreatic proteases is considered to be a crucial event in the early phase of acute pancreatitis but the cause of this activation is not known. Most cases of acute pancreatitis can be attributed to either gallstone disease or alcohol abuse. However, little is known about other risk factors. READ MORE