Search for dissertations about: "cationic liposome"

Showing result 1 - 5 of 6 swedish dissertations containing the words cationic liposome.

  2. 1. Aspects of DNA Strand Exchange: Recombination Proteins and Model System Studies

    Author : Karolin Frykholm; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA strand exchange; cationic liposome; Rad51; Site-Specific Linear Dichroism; RecA; molecular crowding;

    Abstract : DNA recombination is of fundamental importance to all living cells; it is part of the DNA repair machinery and a means to generate genetic diversity. DNA strand exchange, the exchange of strands between homologous DNA molecules, is the central reaction of the recombination process. READ MORE

  4. 2. Antimicrobial Peptide Interactions with Phospholipid Membranes : Effects of Peptide and Lipid Composition on Membrane Adsorption and Disruption

    Author : Adam A Strömstedt; Martin Malmsten; Georges Belfort; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; peptide; adsorption; liposome; membrane; melittin; cholesterol; tryptophan; phospholipid; bilayer; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : The interactions between antimicrobial peptides and phospholipid membranes were investigated, in terms of lipid headgroup variations and the role of cholesterol, as well as peptide composition and structure. Also strategies for increasing proteolytic stability were evaluated. READ MORE

  5. 3. Peptide-Liposome Model Systems for Triggered Release

    Author : Camilla Skyttner; Daniel Aili; Karin Enander; Fredrik Höök; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Liposomes are widely used in drug delivery to improve drug efficacy and to reduce side effects. For liposome-encapsulated drugs to become bioavailable and provide a therapeutic effect they must be released, which typically is a slow process that primarily relies on passive diffusion, liposome rupture or endocytotic uptake. READ MORE

  6. 4. Hyperthermia-responsive liposomal systems

    Author : Yujia Jing; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cationic lipid; asymmetry; phospholipase; liposomes; flip-flop; hyperthermia; phase transition; supported lipid membranes; drug delivery;

    Abstract : Abstract Sophisticated liposomal systems are emerging at an increasing rate to meet the demands for multifunctional drug carriers in chemotherapies in combined with hyperthermia. For example, liposomal drug carriers for temperature-controlled drug release under hyperthermic conditions have recently been tested in clinical trials. READ MORE

  7. 5. Tailormade Surfaces for Extended CE Applications

    Author : Sara Ullsten; Karin Markides; Staffan Folestad; Gerhardus J de Jong; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; capillary electrophoresis; mass spectrometry; surface properties; coatings; polymers; liposomes; proteins; drugs; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : The combination of capillary electrophoresis (CE) and mass spectrometry (MS) constitutes a powerful microanalytical system in the fields of biology, medicine and chemistry. This thesis describes the development of three novel capillary coatings and demonstrates how these extend the utility of CE as a high-efficiency separation technique in protein analysis and biopharmaceutical drug screening. READ MORE