Search for dissertations about: "cd4 cd25 foxp3 regulatory t cells"
Showing result 1 - 5 of 19 swedish dissertations containing the words cd4 cd25 foxp3 regulatory t cells.
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1. Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease
Abstract : Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % and 1-2 %, respectively, of the infected individuals. READ MORE
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2. T cells in chronic obstructive pulmonary disease
Abstract : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. READ MORE
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3. On the induction and function of Foxp3+ regulatory T cells
Abstract : This thesis is based on three original papers with the overall aim to study the mechanisms of induction and function of Foxp3+CD4+CD25+ regulatory T cells. Regulatory T cells induce down-modulation of costimulatory molecules CD80 and CD86 on dendritic cells in vitro. READ MORE
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4. CD25+CD4+ regulatory T cells in rheumatic disease
Abstract : CD25+CD4+ T cells represent a unique cell lineage of thymus derived naturally occurring regulatory T cells. The gene Foxp3 (mouse)/ FOXP3(human) is strictly related to their generation in the thymus and their regulatory function in the periphery. READ MORE
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5. Phenotype and function of CD25+ regulatory T cells in infants and adults
Abstract : Active suppression by CD4+CD25+FOXP3+ regulatory T cells (Treg) is essential for the maintenance of peripheral tolerance to both self antigens and environmental antigens. Absence of these cells in human newborns leads to autoimmune and inflammatory disorders as well as allergic disease. READ MORE