Search for dissertations about: "cd4-cd8 ratio"

Showing result 1 - 5 of 21 swedish dissertations containing the words cd4-cd8 ratio.

2. 1. The Role of Zinc in Leishmaniasis and Tuberculosis

   Author : Miguel Guzman; Tillämpad biokemi; []
   Keywords : Cutaneous leishmaniasis; tuberculosis; zinc supplementation; lymphocytes; cell proliferation; INF-γ; CD4 CD8 ratio;

   Abstract : The synergistic relation between nutritional deficiency and infection may have negative effects on the immune system, making individuals more vulnerable to infection. Zinc can affect the resistance to infections by modulating cytokine release, and by acting as a cofactor of thymulin, which induces the differentiation of immature T lymphocytes. READ MORE

4. 2. Sarcoidosis : inflammatory mechanisms and markers of activity

   Author : Anders Planck; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Sarcoidosis; HLA class II; T-lymphocytes; CD4-CD8 ratio; T cell receptor; angiotensin-converting enzyme; apoptosis;

   Abstract : Sarcoidosis is a disease characterized by an accumulation of CD4+ T-lymphocytes in affected organs. Previous findings of an association between the HLA-allele DR17 and an accumulation in bronchoalveolar lavage fluid (BALF) of CD4+ T-lymphocytes expressing the T-cell receptor (TCR) V gene segment AV2S3, is in line with an aetiological hypothesis claiming that sarcoidosis is elicited by a specific antigen(s) in genetically predisposed individuals. READ MORE

5. 3. Chronic hepatitis B : immunological, virological and clinical aspects in the natural course and during the combined prednisolone and interferon-alpha-2b therapy

   Author : Guo-Zhong Fei; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HBV; IgM and IgG anti-preS2; IgM anti-HBc; CD4 CD8 ratio; lymphocyte subpopulations; HBV DNA; ALT; chronic hepatitis; prednisolone; interferon-alpha;

   Abstract : The aims of this study were to characterize the IgM and IgG antibody responses to well-defined B-cell epitopes within the preS2 region of the HBV envelope proteins in sera from Chinese and Caucasian patients with chronic HBV infection in relation to viral load and liver disease activity. In addition, the effects of the combined prednisolone and interferon- alpha-2b therapy on these parameters, as well as on the peripheral lymphocyte subsets, were studied in Chinese patients with chronic hepatitis B. READ MORE

6. 4. Living and Dying with Primary Sjögren's Syndrome Studies on Aetiology, Treatment, Lymphoma, Survival and Predictors

   Author : Elke Theander; Internmedicin - epidemiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; transplantation; muskelsystem; Skelett; rheumatology locomotion; long-term outcome; Sjögren s Syndrome; Helicobacter pylori infection; prospective cohort studies; SMR; SIR for lymphoproliferative disease; fatigue; health-related quality of life; complement function; oncology; Cytologi; Immunology; cancer; serologi; Immunologi; serology; cancerology; onkologi; reumatologi; muscle system; CD4 T-lymphocytopenia; Cytology;

   Abstract : This work was aimed at improving our understanding of the course of primary Sjögren's syndrome (SS). The Malmö SS patient register and the 2002 American-European Consensus Criteria formed the basis of all studies. Helicobacter pylori (H. READ MORE

7. 5. The Immune System in the Oldest-Old : Clinical and Immunological Studies in the NONA Immune Cohort

   Author : Bengt-Olof Nilsson; Jan Ernerudh; Anders Wikby; Sture Löfgren; Karlis Pauksens; Linköpings universitet; []
   Keywords : Elderly; selection; health status; lymphocyte subsets; CD8; CMV; cytomegalovirus; immune risk; immune risk phenotype; IRP; T-cells; interleukin 6; IL-6; survival; mortality; antinuclear antibodies; ANA; ageing; immunosenescence; MEDICINE; MEDICIN;

   Abstract : The oldest-old (people aged 80 or older) constituted 5 % of the population in Sweden in 2000, an increase from 1.5 % fifty years earlier. The immune system undergoes dramatic changes at high age, sometimes referred to as “immunosenescence”. READ MORE