Search for dissertations about: "cd86"

Showing result 1 - 5 of 53 swedish dissertations containing the word cd86.

  2. 1. Cellular receptors for species B adenoviruses

    Author : Marko Marttila; Niklas Arnberg; Göran Wadell; Tomas Bergström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; CD46; CD80; CD86; Species B; Receptor; Internalization; Infection; Tropism; Virology; Virologi;

    Abstract : Adenoviruses belong to the most common human pathogens. The severity of infection varies greatly, from subclinical to lethal, depending on the virus type and immune status of the infected host. The 51 known human adenovirus serotypes are divided into six species (A-F) based on characteristics such as tropism. READ MORE

  4. 2. Genetic susceptibility to psoriasis in Sweden

    Author : Fredrik Enlund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD80; CD86; joint complaints; linkage analysis; NPL; psoriasis; TDT; chromosome region 3q21;

    Abstract : A common skin disease affecting about 2-3% of the population, psoriasis has an inheritance pattern that is unclear, but most probably many genes are involved in its pathogenesis. Other studies have suggested many susceptibility regions in the genome, but as yet independent studies have replicated only some of these regions located on chromosome 1q, 6p and 17q. READ MORE

  5. 3. The ups and downs of T cells The role of costimulatory molecules in the modulation of T cell responses

    Author : Christina Olsson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; CD28; costimulation; CD152; IL-2; NF-kB; AP-1; superantigen; Immunology; T cell; serologi;

    Abstract : T cell activation requires the combination of antigen in the context of MHC and costimulatory molecules to induce a functional immune response. For our studies, we primarily utilized superantigens (SAg) that bind MHC class II molecules as first signal. READ MORE

  6. 4. Dendritic cell maturation and death during Salmonella infection. Role of pro-inflammatory cytokines and MyD88

    Author : Malin Sundquist; Göteborgs universitet; []
    Keywords : Dendritic cells; Costimulatory molecules; Bacterial infection; Pro-inflammatory cytokines; Toll-like receptors; Ag presentation; Cell death;

    Abstract : The costimulatory molecules CD80 and CD86 are required for the ability of dendritic cells (DC) to induce both tolerance and immunity. This thesis investigates the control of CD80/CD86 upregulation in vivo on DC during Salmonella infection. READ MORE

  7. 5. Mechanisms of dendritic cell maturation induced by intracellular bacteria infection

    Author : Miguel A. Tam; Göteborgs universitet; []
    Keywords : Listeria; Salmonella; dendritic cells; maturation; MyD88; IFN-? ?;

    Abstract : Dendritic cells (DCs) are essential for the development of an immune response against pathogens such as Listeria monocytogenes and Salmonella typhimurium. This is mostly because of their unique capacity to stimulate naïve T cells. READ MORE