Search for dissertations about: "cebpa"

Showing result 1 - 5 of 8 swedish dissertations containing the word cebpa.

  2. 1. Not just a pipe's dream : plumbing the contribution of cell diversity to oesophageal homeostasis

    Author : David Grommisch; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epithelial barrier tissues like the skin, intestine, and oesophagus form a physical barrier that protects our body from external threats. To accurately fulfil their function, epithelial barriers are subject to constant epithelial cell renewal throughout our lifespan. READ MORE

  4. 2. Deciphering the Pathogenesis of Acute Myeloid Leukemia

    Author : Kristian Reckzeh; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Hematopoietic Stem Cell; AML; FLT3; C EBPalpha;

    Abstract : Acute myeloid leukemia (AML) is a malignant disorder of the blood system. Hematopoietic stem cells (HSCs) supply and maintain this system by differentiating via intermediates into lineage-restricted progenitors that strongly proliferate to keep up with the high turn-over of mature blood cells. READ MORE

  5. 3. An exPADItion for citrullination in the developing hair follicle

    Author : Kim Vikhe Patil; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During epidermal development, to assure proper tissue structure, highly complex transcriptional networks interact within the stem cell compartments of the epidermis and hair follicles (HFs) to balance the choice between self-renewal or differentiation. The full characterisation of the protein profiles resulting from those transcriptional networks, within the compartments of the HF, remains, however, incomplete. READ MORE

  6. 4. Intracellular signaling in the lung : a role for C/EBP transcription factors in chronic obstructive pulmonary disease, glucocorticoid signaling and lung development

    Author : Lukas Didon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Over the last decade, a previously unknown role has been established for members of the C/EBP transcription factor family in lung gene expression. In other organs, C/EBPs are well known regulators of cell differentiation and linked processes such as proliferation, apoptosis, gene expression as well as central regulators of inflammatory responses and infectious defenses. READ MORE

  7. 5. C/EBP transcription factors in lung cellular differentiation and development

    Author : Tove Berg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : C EBP transcription factors; lung; development; differentiation; glucocorticoid regulation;

    Abstract : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. READ MORE