Search for dissertations about: "cell communication physiology"

Showing result 6 - 10 of 16 swedish dissertations containing the words cell communication physiology.

  2. 6. Mitochondria-endoplasmic reticulum contacts in neuronal cells : from physiology to therapeutics

    Author : Giacomo Dentoni; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mitochondria and the endoplasmic reticulum (ER) are intracellular organelles that play vital physiological functions. Mitochondria are key players in energy production through adenosine triphosphate (ATP) production and calcium (Ca2+) buffering, while the ER is involved in protein and lipid synthesis along with Ca2+ signalling in the cell. READ MORE

  4. 7. Integrating bioinformatics and physiology to describe genetic effects in complex polygenic diseases

    Author : Hemang Parikh; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin sensitivity; Type 2 diabetes mellitus; Skeletal muscle; Gene expressionprofiling; TXNIP; Maximal oxygen uptake; Type 1 fibers; NDUFB5; CPT1B; ATP5C1; AHNAK; CAST; Genome-wide association studies.;

    Abstract : Type 2 diabetes mellitus (T2DM) results from interaction between genetic and environmental factors. The worldwide prevalence of T2DM is increasing rapidly due to reduction in physical activity, increase in dietary intake, and the aging of the population. READ MORE

  5. 8. A tripartite of immune-, epithelial-, and nervous-systems in the homeostatic regulation of the gut

    Author : Song Hui Chng; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Various cell types in the intestinal mucosa are constantly exposed to complex signals emanating from the lumen, including the microbiota and its metabolites. How these bilateral interactions in turn influences intestinal homeostasis is an important question in order to understand microbiota-host interactions. READ MORE

  6. 9. Systems Analysis of the Protein Secretory Pathway in Yeast and Human Cells

    Author : Amir Feizi; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein production; flux balance analysis; biopharmaceutical; secretory pathway: secretome; recombinant protein; genome-scale modeling; systems biology;

    Abstract : The cell was discovered by Robert Hooke in 1665, later in nineteen century the cell theory was developed as all organisms are composed of one or more cells. Since then, many tools and experimental methods have been developed to dissect and characterize the cell components which resulted in established solid scientific fields such as biochemistry, molecular cell biology and genetics. READ MORE

  7. 10. Development of sensitive cellular assay systems and their application to the identification of "orphan" seven-transmembrane receptors

    Author : Knut Kotarsky; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemi; Metabolism; Biochemistry; metabolism; leukotrieneB4; thiazolidinedione; 9-HODE; fatty acid; luciferase; GFP; reporter gene; preclinical assay; receptor; GPCR;

    Abstract : Seven-transmembrane, G-protein coupled receptors play a central role in physiology since they facilitate cell communication in multicellular organisms by recognition of a broad range of ligands. They also represent important drug targets. READ MORE