Search for dissertations about: "cell cultures"

Showing result 21 - 25 of 692 swedish dissertations containing the words cell cultures.

  2. 21. Gene expression studies of pregastrulation development: the basement membrane is essential for cell differentiation

    Author : Mikael Åkerlund; Muskelbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscular dystrophy; development; Basement membrane; laminin; stem cells; FGF;

    Abstract : Basement membranes (BMs) are sheet-like structures of extracellular matrix. They act as a supporting structure but can also significantly influence cellular behavior in development, tissue homeostasis and disease. Laminins, a major BM component, are multidomain proteins, consisting of three polypeptide chains (α, β and γ). READ MORE

  4. 22. Vγ9Vδ2 T cells - response to P. falciparum-derived phosphoantigens and potential for use in colon cancer immunotherapy 

    Author : Chenxiao Liu; Ingela Parmryd; Susanna Cardell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Vγ9Vδ2 T cell is the dominant circulating γδ T cell subset in humans, can expand massively upon malaria infection and are cytotoxic to cancer cells. Vγ9Vδ2 T cells are stimulated by phosphoantigens, primarily isoprenoid pyrophosphates like isopentenyl pyrophosphate and (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP). READ MORE

  5. 23. Modeling glioblastoma heterogeneity to decipher its biology

    Author : Yuan Xie; Lene Uhrbom; Massimo Squatrito; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma multiforme; biobank; GBM cells; cell of origin; LGR5; OPCs;

    Abstract : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. READ MORE

  6. 24. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification

    Author : Di Yu; Magnus Essand; Dirk Nettelbeck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; cancer; therapy; neuroblastoma; neuroendocrine; modification; Tat; PTD; cell penetrating peptide; Helicobacter pylori; NAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Klinisk virologi; Clinical Virology; Medical Virology; Medicinsk virologi; Molekylär medicin; Molecular Medicine; Molekylär bioteknik; Molecular Biotechnology;

    Abstract : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. READ MORE

  7. 25. Characterisation of mammalian cell culture processes with NIR spectroscopy

    Author : Per Sivertsson; KTH; []
    Keywords : near-infrared NIR spectroscopy; cell culture; mammalian cell culture; characterisation; glucose; lactate; ammonia; cell content; viability; multivariate analysis; principal component analysis PCA ; partial least squares regression PLS ; score plo;

    Abstract : The importance of recombinant proteins produced by mammaliancell culture has increased dramatically due to the discoveriesin the field of recombinant biotechnology. Therefore,optimising and gaining process knowledge about cell culture hasalso gained in interest. READ MORE