Search for dissertations about: "cell detection"

Showing result 16 - 20 of 635 swedish dissertations containing the words cell detection.

  1. 16. Improvements and Applications of in situ Proximity Ligation Assays

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Karin Grannas; Uppsala universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molekylär medicin; Molecular Medicine;

    Abstract : The cells building up the human body is in constant communication with each other. This communication is done through large complex networks of signaling pathways for inter- and intracellular signal transduction. The signaling activity regulates many important processes, for example cell death, proliferation and differentiation. READ MORE

  2. 17. Development of DNA-based methods for analysis of protein interactions

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Axel Klaesson; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; In situ proximity ligation assay PLA ; rolling circle amplification RCA ; Hybridization chain reaction HCR ; proxHCR; Oligonucleotide design; Protein-protein interactions; Post-translational modifications.; Farmaceutisk vetenskap; Pharmaceutical Science; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : In situ proximity ligation assay (PLA) is a method for detection of protein interactions, post-translational modifications (PTMs) and individual proteins that allows information about their localization in a cell or tissue to be extracted. The method is based on oligonucleotide-conjugated antibodies (proximity probes) that upon binding of two epitopes in close proximity give rise to an amplifiable DNA circle. READ MORE

  3. 18. Application of Padlock Probe Based Nucleic Acid Analysis In Situ

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sara Henriksson; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probe; rolling circle amplification; single cell gel electrophoresis assay; comet assay; Crimean Congo hemorrhagic fever virus; MEDICINE Morphology; cell biology; pathology Pathology Molecular medicine; MEDICIN Morfologi; cellbiologi; patologi Patologi Molekylär medicin; Molekylär medicin; Molecular Medicine;

    Abstract : The great variation displayed by nucleic acid molecules in human cells, and the continuous discovery of their impact on life, consequently require continuous refinements of molecular analysis techniques. Padlock probes and rolling circle amplification offer single nucleotide discrimination in situ, a high signal-to-noise ratio and localized detection within cells and tissues. READ MORE

  4. 19. Integration of Molecular Biology and Morphology in Effusions with Focus on in situ Detection of Telomerase and its Components

    University dissertation from Faculty of Medicine, Lund University

    Author : Nooreldin Zendehrokh; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; Patologi allmän ; patologisk anatomi; Diagnostics; Diagnostik; cancer; TRAP in situ; onkologi; Cytologi; cancerology; oncology; Cytology; Medicin människa och djur ; Medicine human and vertebrates ; General pathology; Telomerase;

    Abstract : Popular Abstract in Swedish Den viktigaste uppgiften inom den kliniska cytologin är att påvisa cancerceller i olika typer av cellprover. Många olika cancertumörer sprider sig till lungsäcken och bukhålan och ger då ofta upphov till vätska (exsudat) som innehåller cancerceller. READ MORE

  5. 20. Detection and characterization of novel proteins in Trypanosoma cruzi

    University dissertation from Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Author : Marcela Ferella; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. READ MORE