Search for dissertations about: "cell detection"

Showing result 21 - 25 of 643 swedish dissertations containing the words cell detection.

  1. 21. Detection and characterization of novel proteins in Trypanosoma cruzi

    University dissertation from Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Author : Marcela Ferella; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. READ MORE

  2. 22. Minimal Residual Disease Assessment in Childhood Acute Lymphoblastic Leukemia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ingrid Thörn; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood acute lymphoblastic leukemia; minimal residual disease; IG TCR gene rearrangements; BCR-ABL1 fusion gene transcripts; real-time quantitative PCR; multicolor flow cytometry; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi; Pathology; patologi;

    Abstract : Traditionally, response to treatment in hematological malignancies is evaluated by light microscopy of bone marrow (BM) smears, but due to more effective therapies more sensitive methods are needed. Today, detection of minimal residual disease (MRD) using immunological and molecular techniques can be 100 times more sensitive than morphology. READ MORE

  3. 23. Validation of antibodies for protein profiling A study using immunohistochemistry on tissue microarrays

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Linda Paavilainen; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody validation; monospecific antibodies; protein profiling; immunohistochemistry; tissue microarrays; western blot; fixatives; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi; Pathology; patologi;

    Abstract : The field of proteomics has rapidly expanded due to the completion of the human genome sequence. This thesis validates affinity-purified monospecific antibodies of polyclonal origin, for protein profiling in a broad spectrum of normal tissues and cells. READ MORE

  4. 24. Genotyping and Mutation Detection In Situ Development and application of single-molecule techniques

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ida Grundberg; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; padlock probes; in situ; rolling circle amplification; mRNA; genotyping; mutation detection; cancer; tissue sections; diagnostics; single-molecule; single-cell; microscopy; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Molecular medicine genetics and pathology ; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

    Abstract : The human body is composed of trillions of cells closely working together to maintain a functional organism. Every cell is unique in molecular composition and can acquire genetic variations that might cause it to turn pathological. READ MORE

  5. 25. Oncolytic Adenovirus Therapy of Neuroendocrine Tumors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Justyna Leja; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenovirus; virotherapy; oncolytic virus; neuroendocrine tumors; chromogranin A; somatostatin receptors; microRNA; novel biomarkers; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics Molecular biology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik Molekylärbiologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; MEDICINE Microbiology; immunology; infectious diseases Microbiology Virology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Virologi; MEDICINE Morphology; cell biology; pathology Morphology Tumour biology; MEDICIN Morfologi; cellbiologi; patologi Morfologi Tumörbiologi; Medical Science; Medicinsk vetenskap; Oncology; Onkologi; Medical Virology; Medicinsk virologi; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Neuroendocrine tumors (NETs), originally described as carcinoids, represent a rare and heterogeneous group of neoplasms associated with intensive secretion of hormones, bioactive peptides and amines. Most of the patients are diagnosed at a late stage of disease, often with liver metastases. READ MORE