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Showing result 6 - 10 of 765 swedish dissertations matching the above criteria.
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6. Single-molecule Detection in situ
Abstract : The human body contains a variety of different cell types that share a common genome, but differ in how they use the information encoded therein. Variation in molecular content exists even at the level of individual cells, and to provide deeper insight into complex cellular processes methods that permit analysis of each cell on its own are needed. READ MORE
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7. DNA methylation in T cell leukaemia
Abstract : T cell acute lymphoblastic leukaemia (T-ALL) is a predominantly paediatric cancer that stems from malignant transformation of developing T cells. While the disease has an overall survival rate of 80%, the intense chemotherapy treatment causes severe toxicity and long-term side effects. READ MORE
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8. Droplet microfluidics for single cell and nucleic acid analysis
Abstract : Droplet microfluidics is an emerging technology for analysis of single cells and biomolecules at high throughput. The controlled encapsulation of particles along with the surrounding microenvironment in discrete droplets, which acts as miniaturized reaction vessels, allows millions of particles to be screened in parallel. READ MORE
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9. Ultrasonic Fluid and Cell Manipulation
Abstract : During the last decade, ultrasonic manipulation has matured into an important tool with a wide range of applications, from fundamental cell biological research to clinical and industrial implementations. The contactless nature of ultrasound makes it possible to manipulate living cells in a gentle way, e.g. READ MORE
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10. Pitfalls in β-cell ion imaging with fluorescent indicators and their use for real-time detection of somatostatin secretion
Abstract : Fluorescent ion indicators have become indispensable tools in cell physiology. Dye indicators can easily be loaded into most types of cells, while genetically encoded indicators are advantageous in allowing specific cellular or subcellular targeting. READ MORE