Search for dissertations about: "cell factories"

Showing result 11 - 15 of 52 swedish dissertations containing the words cell factories.

  1. 11. Metabolite biosensors for cell factory development

    Author : Yasaman Dabirian; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; malonyl-CoA; metabolite-responsive transcription factor-based biosensors; Saccharomyces cerevisiae; alkanes; fatty acyl-CoA; synthetic biology;

    Abstract : Through synergy with natural sciences and engineering disciplines, biotechnology has become a broad, interdisciplinary, scientific field with many applications. One such application is the sustainable production of industrially relevant products using living systems such as microorganisms. READ MORE

  2. 12. SYSBIOMICS of Aspergilli: SYStems Biology, BIoinformatics and OMICS analysis of Aspergilli cell factories

    Author : Wanwipa Vongsangnak; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Systems Biology; Aspergilli; Bioinformatics; Omics analysis;

    Abstract : Aspergilli represent a group of filamentous fungi that plays a key role in industrialbiotechnology, and as human, animal and plant pathogens. Here three Aspergillus species,namely Aspergillus oryzae, Aspergillus niger and Aspergillus nidulans are considered. READ MORE

  3. 13. Microbial Production of Bio-Based Chemicals: A Biorefinery Perspective

    Author : Tarek Dishisha; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biorefinery; platform chemical; organic acid; propionic acid; 3-hydroxypropionic acid; 3-hydroxypropionaldehyde; methacrylic acid; 1; 3-propanediol; Propionibacterium acidipropionici; Lactobacillus reuteri; Gluconobacter oxydans; high cell density fermentation; biotransformation; product inhibition; cell recycle; immobilized cells; chemical catalysis; pdu operon;

    Abstract : A shift from fossil- to renewable biomass feedstock for the emerging bio-based economy requires the development and adoption of new sustainable technologies that are more suited for transformation of biomass components to chemicals, materials and energy. This thesis presents investigations on the development of processes based on industrial biotechnology as a key element for the production of chemicals from agro-/industrial by-products. READ MORE

  4. 14. Strategies to improve and balance the expression levels of recombinant proteins in mammalian cell lines

    Author : Mona Moradi Barzadd; Johan Rockberg; Alan Dickson; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CHO; HEK293; Aggregation; Bispecific; Cancer assay; Cell line engineering; sulfatase; biologics; transcriptomic; Biotechnology; Bioteknologi;

    Abstract : Proteins are the building blocks of all living organisms enabling us to function and survive. There are more than 100,000 different proteins in the human body performing a variety of vital tasks. READ MORE

  5. 15. Metabolic engineering of S. cerevisiae for the production of flavonoids

    Author : Marta Tous Mohedano; Chalmers tekniska högskola; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microbial cell factories; high-value products; sustainability; cinnamic acid; plant natural products; Genetic engineering; yeast;

    Abstract : The interest in the production of natural products such as flavonoids has been increasing during the last decade. Flavonoids have several attractive bioactivities including antitumoral, antioxidant or antimicrobial properties. To produce these high-value products, we usually recur to chemical synthesis or plant extraction. READ MORE