Search for dissertations about: "cell factories"

Showing result 11 - 15 of 24 swedish dissertations containing the words cell factories.

  1. 11. The Cyanobacterial Uptake Hydrogenase Regulation, Maturation and Function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marie Holmqvist; Uppsala universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biohydrogen; CalA; Cyanobacteria; Hydrogenase; Maturation; Nostoc punctiforme ATCC 29133; Nostoc sp. PCC 7120; Transcriptional regulation; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; NATURAL SCIENCES Chemistry Biochemistry Molecular biology; NATURVETENSKAP Kemi Biokemi Molekylärbiologi; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

    Abstract : With accellerating global warming and pollution problems a change of energy regime is necessary. Solar energy offers a clean and unlimited energy source of enormous potential. Due to it’s intermittenet nature solar energy must be stored - ideally in the chemical bond of a carrier molecule. READ MORE

  2. 12. Metabolic Engineering of Recombinant Protein Production by Saccharomyces cerevisiae

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Zihe Liu; [2012]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; recombinant protein production; genome sequencing; DNA microarray; insulin precursor; growth rate; UV mutation; yeast; anaerobic electron acceptor; secretory pathway; unfolded protein response; metabolic engineering; systems biology; α-amylase;

    Abstract : The yeast Saccharomyces cerevisiae is a widely used cell factory for the production of fuels, chemicals, and it also provides a platform for the production of many heterologous proteins of medical or industrial interest. In this thesis, random and rational approaches, such as vector design, host engineering, fermentation analysis, UV Mutation, coupled with high-throughput systems biology techniques (including whole genomic sequencing, microarray analysis and flux analysis) and integrated analysis (Reporter feature technique), were employed to engineer cellular properties more effectively and purposefully to construct cell factories for protein production. READ MORE

  3. 13. Metabolic Engineering of Central Carbon Metabolism in Saccharomyces cerevisiae The contribution of systems biology to physiological studies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marta Papini; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fermentation technology; Metabolic engineering; RNA-sequencing; Saccharomyces cerevisiae; DNA microarrays; 13Cbased flux analysis; system biology; Scheffersomyces stipitis;

    Abstract : Saccharomyces cerevisiae is one of the most well characterized yeast of large industrial interest due to several attractivefeatures such as its capability to efficiently convert glucose into ethanol and carbon dioxide at high flux, its amenabilityto genetic modification and the presence of extensive knowledge databases. For these reasons, it is often considered asuitable cell factory for the production of different classes of compounds. READ MORE

  4. 14. Systems Biology of Recombinant Protein Production by Fungi

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lifang Liu; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Systems biology has emerged as a highly potent tool for studying biological processes over the last decades. However, its application to complex metabolic processes such as protein secretion is still at the infant stage. READ MORE

  5. 15. Droplet microfluidics for directed evolution of biocatalysts

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Staffan Sjöström; KTH.; [2015]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Droplet microfluidics; Enzymes; directed evolution; high throughput screening; Biotechnology; Bioteknologi;

    Abstract : Biocatalysts, biologically derived catalysts, are of great importance for a wide range of industrial applications. They are used in the production of for example foods, pharmaceuticals and biofuels. Improving biocatalysts commonly relies on directed evolution, i.e. READ MORE