Search for dissertations about: "cell factory"

Showing result 1 - 5 of 43 swedish dissertations containing the words cell factory.

  2. 1. Biobased Adipic Acid - Challenges in Establishing a Cell Factory

    Author : Emma Skoog; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; 2-hexenedioic acid; enzyme engineering; 6-aminohex-2-enoic acid; S. cerevisiae; adipic acid pathway via lysine; cell factory; C. viswanathii; lignocellulose; biorefinery; tolerance; in silico docking; adipic acid;

    Abstract : Growing concern regarding climate change calls for sustainable solutions to significantly reduce our dependency on non-renewable fossil-based raw materials. One potential solution is the development of biorefineries where biobased, renewable raw materials are converted into valuable products via enzymatic, chemical or microbial conversion. READ MORE

  4. 2. Evolution of cellular complexity and other remarkable features in Gemmataceae : Complex bacterial lineages defy prokaryotic trends

    Author : Mayank Mahajan; Siv G. E. Andersson; James O. McInerney; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular evolution; Planctomycetes; Gemmataceae; functional organization; signalling; protein interaction; peptidoglycan; membranes; cell division; radiation tolerance; Pfam; SCOP; comparative genomics; protein architecture; domain shuffling and orthologous clustering; Bioinformatics; Bioinformatik; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Bacteria of the family Gemmataceae belong the phylum Planctomycetes and are remarkable because of their complex cellular architectures, previously considered to be traits exclusive to eukaryotes. This thesis provides clues to the atypical cell envelope, the enhanced radiotolerance and the amazing cellular complexity of these bacteria. READ MORE

  5. 3. Towards membrane engineering as a tool in cell factory design: A case study on acetic acid tolerance in Saccharomyces cerevisiae

    Author : Lina Lindahl; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; butanol; inhibitors; lipidomics; Key words: Lignocellulose; Zygosaccharomyces bailii; molecular dynamics simulations; membrane permeability; carbon-14 uptake; ethanol; robustness;

    Abstract : The sustainable production of fuels, chemicals, and materials using renewable resources is a necessity if we are to reduce our ecological footprint and the rate of climate change. Lignocellulosic biomass, the major constituent of plant cell walls, is a renewable raw material with great potential due to its high abundance. READ MORE

  6. 4. Ribosomal proteins L5, L15 and elongation factor 2, three vital components of the translation machinery : Functional features of RPL5, RPL15 and EF2 from Saccharomyces cerevisiae studied in vivo

    Author : Hossein Moradi; Roger Karlsson; Odd Nygård; Anders Liljas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Ribosomal protein; Elongation factor; Translation; Cell Biology; cellbiologi;

    Abstract : Protein synthesis is an essential, energy consuming and tightly regulated process in all living cells. A central core of the cellular protein-factory is a macromolecule called ribosome. Ribosomes are composed of ribosomal RNAs (rRNAs) and proteins (RPs). Additional components such as elongation factors (EFs) also contribute to this process. READ MORE

  7. 5. Droplet microfluidics for single cell and nucleic acid analysis

    Author : Prem Kumar Periyannan Rajeswari; Helene Andersson Svahn; Håkan Jönsson; Martin Dufva; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Biomarker detection; Cell behavior analysis; Cell factories; Droplet microfluidics; Droplet PCR; High throughput biology; Label-free enrichment; Single cell analysis; Bioteknologi; Biotechnology;

    Abstract : Droplet microfluidics is an emerging technology for analysis of single cells and biomolecules at high throughput. The controlled encapsulation of particles along with the surrounding microenvironment in discrete droplets, which acts as miniaturized reaction vessels, allows millions of particles to be screened in parallel. READ MORE