Search for dissertations about: "cell penetrating peptide"
Showing result 1 - 5 of 69 swedish dissertations containing the words cell penetrating peptide.
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1. Cell-penetrating peptides : an uptake mechanism & a new endosomolytic peptide
Abstract : Peptide-based drugs have slowly begun migrating from laboratories into pharmacies and now there are several on the market. However, currently only one gene based therapy that is relies on a viral delivery vector has been approved. READ MORE
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2. Cell-penetrating peptide targeting mitochondria : Design, synthesis, characterization, and biological effects
Abstract : More than twenty years after the discovery of the first cell-penetrating peptide (CPP), a large number of both naturally occurring as well as engineered CPPs have been discovered. Generally, CPPs are short polycationic sequences of less than 30 amino acids that are able to translocate different cargoes into cells. READ MORE
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3. Cell-penetrating peptides : Uptake mechanism and the role of receptors
Abstract : Genes are the major regulators of biological processes in every living thing. Problems with gene regulation can cause serious problems for the organism; for example, most cancers have some kind of genetic component. Regulation of biological processes using oligonucleotides can potentially be a therapy for any ailment, not just cancer. READ MORE
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4. Cell-penetrating peptides : Uptake, stability and biological activity
Abstract : Cell-penetrating peptides (CPPs) have emerged as a group of remarkable delivery vectors for various hydrophilic macromolecules, otherwise excluded from cells due to the protective plasma membrane. Unbiased conclusions regarding e.g. READ MORE
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5. CELL PENETRATING PEPTIDES : CHEMICAL MODIFICATION AND FORMULATION DEVELOPMENT
Abstract : Cell penetrating peptides (CPPs) have been extensively studied and exploited as drug delivery vectors for a wide variety of therapeu-tic cargos. However, several issues remain to be addressed regarding the enhancement of their efficiency and stability. READ MORE