Search for dissertations about: "cell separation"

Showing result 11 - 15 of 268 swedish dissertations containing the words cell separation.

2. 11. Cytokine Regulation of Hematopoietic Stem Cells and Lymphopoiesis

   Author : Natalija Buza-Vidas; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; lineage commitment; cytokines; lymphopoiesis; extracellulära vätskor; transplantation; hematopoietic stem cells;

   Abstract : Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). READ MORE

4. 12. Glutathione in the brain. Studies on efflux and possible implications in neurotoxicity

   Author : Camilla Wallin; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glutathione; excitotoxicity; hypoxia-ischemia; brain; rat; anoxia-aglycemia; g-glutamyl transpeptidase; glutamate; NMDA; oxidative stress; mitochondria; amino acids;

   Abstract : Neuronal cell death in acute insults such as stroke, trauma and epilepsy involves overactivation of glutamate receptors, calcium influx and increased formation of potentially toxic reactive oxygen species. Glutathione is a key component in the antioxidant defense system against reactive oxygen species. READ MORE

5. 13. On acoustic particle and cell manipulation in microfluidic systems

   Author : Filip Petersson; Avdelningen för Biomedicinsk teknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medicin människa och djur ; Natural science; Naturvetenskap; Technological sciences; Teknik; acoustic particle manipulation standing wave; acoustic radiation force; laminar flow; Medicine human and vertebrates ; microparticles; ultrasound; lab-on-a-chip; µ-TAS; separation; cells; microfabrication; microtechnology; microfluidics;

   Abstract : The combination of laminar flows in microfabricated channels and acoustic forces induced in ultrasonic standing wave fields offers new possibilities for advanced particle and cell manipulation in lab-on-a-chip applications as well as in relatively high throughput applications. Acoustic particle manipulation systems can be used e.g. READ MORE

6. 14. Magnetic bead-based isolation of biological therapeutic modalities

   Author : Nils A. Brechmann; Véronique Chotteau; Nigel Titchener-Hooker; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic bead separation; Magnetic beads; Protein A; Protein G; Negative cell isolation; Monoclonal antibody; induced pluripotent stem cells; human mesenchymal stem cells; Allogenic cell therapy; Biomanufacturing; cell clarification; Biotechnology; Bioteknologi;

   Abstract : Biopharmaceutical modalities, such as monoclonal antibodies or the less established cell therapies, are nowadays very important for the treatment of severe or incurable diseases. The manufacturing of such modalities is complex and costly, including the downstream processing, which is highly essential to ensure the safety and quality of the product. READ MORE

7. 15. Droplet microfluidics for screening and sorting of microbial cell factories

   Author : Sara Björk; Helene Svahn Andersson; Håkan Jönsson; Christoph Merten; KTH; []
   Keywords : Droplet microfluidics; Cell factories; High-throughput screening; Cell culture; Bioteknologi; Biotechnology;

   Abstract : Cell factories are cells that have been engineered to produce a compound of interest, ranging from biopharmaceuticals to biofuels. With advances in metabolic engineering, the number of cell factory variants to evaluate has increased dramatically, necessitating screening methods with increased throughput. READ MORE