Search for dissertations about: "cell-cycle progression"

Showing result 1 - 5 of 221 swedish dissertations containing the words cell-cycle progression.

  2. 1. The Polyamine Dependence of Cell Cycle Progression-Application in Breast Cancer Treatment

    Author : Louise Myhre; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tissue culture; histochemistry; Histology; cytochemistry; onkologi; cancer; Cytologi; oncology; cancerology; Cytology; cell cycle kinetics; cell cycle regulatory proteins; polyamine analogues; DENSPM; CGP48664; DFMO; cell cycle regulation; Polyamines; breast cancer; Djurfysiologi; Animal physiology; vävnadskultur; Histologi; cytokemi; histokemi;

    Abstract : In the normal functioning organism, there is a balance between cell proliferation, cell differentiation, and cell death. An imbalance in these processes results in different diseases. This thesis concerns the imbalance where there is too little cell death and cell differentiation with increased cell proliferation. READ MORE

  4. 2. Cell cycle regulation in cancer: A noncoding perspective

    Author : Mohamad Ali; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long Noncoding RNA; lncRNA; Cell cycle; S phase; Mitosis; Checkpoint; Cancer; SCAT7; LY6K-AS;

    Abstract : The cell cycle progression is tightly regulated to ensure error-free cell replication. The complexity of the transcriptional machinery aids to function in a spatiotemporal pattern across different phases and genomic loci. READ MORE

  5. 3. The cell cycle of the hyperthermophilic archaeal genus Sulfolobus

    Author : Karin Hjort; Patrick Dennis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Cell cycle; Sulfolobus; Archaea; Origin; Replication; SIRV2; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; mikrobiologi; Microbiology;

    Abstract : The third domain of life, Archaea is one of the three main evolutionary lineages together with the Bacteria and the Eukarya domains. The archaea are, despite their prokaryotic cell organisation, more closely related to eukaryotes than to bacteria in terms of the informational pathways (DNA replication, transcription and translation). READ MORE

  6. 4. Effects of polyamine pool manipulation on genes expressed during the cell cycle

    Author : Pia Berntsson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Animal physiology; cyclin A; ODC; MCF-7; mitotic shake off; DENSPM; CHO; cDNA microarray; cell cycle; spermine; Djurfysiologi; AdoMetDC; 2D gel electrophoresis; polyamines; spermidine; putrescine;

    Abstract : The polyamines - putrescine, spermidine and spermine - are polycations found within cells. They have been shown to be essential for optimal cell proliferation and cell survival. Cells maintain their polyamine levels in a well-regulated system involving biosynthesis, catabolism and uptake/excretion. READ MORE

  7. 5. Coping with Stress : Regulation of the Caulobacter crescentus cell cycle in response to environmental cues

    Author : Kristina Heinrich; Kristina Jonas; Emanuele Biondi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Caulobacter crescentus; bacteria; cell cycle; stress; filamentation; cell morphology; DNA replication; cell division; molekylär biovetenskap; Molecular Bioscience;

    Abstract : All organisms have to respond to environmental changes to maintain cellular and genome integrity. In particular, unicellular organisms like bacteria must be able to analyze their surroundings and rapidly adjust their growth mode and cell cycle program in response to environmental changes, such as changes in nutrient availability, temperature, osmolarity, or pH. READ MORE