Search for dissertations about: "cell"

Showing result 1 - 5 of 10466 swedish dissertations containing the word cell.

  1. 1. Creating cell microenvironments in vitro

    Author : Patric Wallin; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell migration; lipid bilayers; cell differentiation; liquid handling; surface functionalization; Microfluidics; chemotractant gradients; mammalian cell culture; cell microenvironments; in vitro screening assay;

    Abstract : Stem cells have a great potential to bring about advancements in fields like developmental biology, drug discovery, cancer biology and tissue engineering. In order to be able to use stem cells to their full potential, it is important to have control over their behavior. READ MORE

  2. 2. Effects of adenosine and acetylcholine on the lacrimal gland

    University dissertation from Växjö, Kalmar : Linnaeus Univeristy Press

    Author : Stina K. Carlsson; J. Peter Gierow; Sven Tågerud; Darlene Dartt; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Lacrimal gland; adenosine; adenosine receptors; signal transduction; exocrine secretion; tear film; dry eye; Sjögren’s syndrome; acetylcholine; mitogen activated protein kinase; p38; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; MEDICINE Physiology and pharmacology Ophtalmology; MEDICIN Fysiologi och farmakologi Oftalmologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Cell biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; Biomedicinsk vetenskap; Biomedical Sciences;

    Abstract : A balanced tear film is essential for a healthy ocular surface. Insufficient tear production may result in dry eye, a common disorder in the elderly population. Dry eye causes significant discomfort in the patients and may lead to visual impairment and ocular infections. READ MORE

  3. 3. Pancreatic extracellular communication. Applications to beta cell cultures and islet amyloid polypeptide aggregation

    University dissertation from Gothenburg : Chalmers tekniska högskola

    Author : Diana Ribeiro; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in vitro pancreatic models; induced pluripotent stem cells; stem cell differentiation; insulin; 3D-culture; extracellular vesicles; glucose-stimulated insulin secretion; islet amyloid polypeptide; type 2 diabetes mellitus; extracellular matrix; adipose-derived stem cells; Diabetes mellitus; protein aggregation;

    Abstract : Diabetes mellitus (DM) is a disease with epidemic proportions due to increased incidences worldwide, persistence of undiagnosed cases, uncontrolled forms of the disease, association with cardiovascular complications, and lack of definitive treatment options. In particular, type 2 DM (T2DM) is placing an enormous financial burden on worldwide healthcare systems that will increase in the futureThere is a need to develop physiological assay platforms that provide functionally relevant models of diabetes in order to accelerate the discovery of new treatments. READ MORE

  4. 4. α-Cell signalling in glucose-regulated glucagon secretion

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Qian Yu; Anders Tengholm; Erik Gylfe; Sebastian Barg; David W Piston; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islets; glucagon; insulin; somatostatin; ATP; cAMP; Ca2 ; GHB; oscillations; α-cell; β-cell; δ-cell; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Glucagon is a blood glucose-elevating hormone released from α-cells in the islets of Langerhans during hypoglycaemia. Glucagon is critical for glucose homeostasis and inappropriate regulation of its secretion underlies both impaired counter-regulation of hypoglycaemia and chronic hyperglycaemia in diabetes patients. READ MORE

  5. 5. Studies of neuropeptides in pancreatic beta cell function with special emphasis on islet amyloid polypeptide (IAPP)

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ella Karlsson; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; alpha cell; amylin; beta cell; chromogranin; growth; IAPP; insulin; islet amyloid polypeptide; leptin; NOD mice; pancreastatin; pancreatic islet; proliferation; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : The presence of protein amyloid in pancreas and its association to diabetes was first described 100 years ago in 1901, but was not identified as Islet Amyloid Polypeptide (IAPP) until 1986. The aim of the present work was to determine the role of the beta cell hormone, IAPP, in normal pancreatic islet physiology and during early disturbances of islet function. READ MORE