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Showing result 1 - 5 of 812 swedish dissertations matching the above criteria.

  2. 1. Regulation of a Transcription Factor Activating Protease

    Author : Deike J. Omnus; Per O. Ljungdahl; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Latent Transcription Factors; Protease; Phosphorylation; Proteasome; Signal Transduction; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Abstract : .... READ MORE

  4. 2. Application of a New Logic to Old Drugs: Angiogenesis Inhibition in Neuroblastoma

    Author : Åsa Svensson; Rolf Christofferson; Per Kogner; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; angiogenesis; neuroblastoma; CHS 828; digoxin; combination treatment; Cellbiologi; Cell biology; Cellbiologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Neuroblastoma is one of the most common solid cancers of early childhood. In Sweden, approximately 10-15 cases occur annually. The overall five-year neuroblastoma survival in Europe is approximately 45%. Since cancer treatment involves drugs with risks of side effects in the growing child, there is a need for more effective and less toxic drugs. READ MORE

  5. 3. Elongation factor 2: A key component of the translation machinery in eukaryotes : Properties of yeast elongation factor 2 studied in vivo

    Author : Galyna Bartish; Odd Nygård; Suparna Sanyal; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Elongation factor 2; yeast; ribosome; phosphorylation; Switch I; site-directed mutagenesis; functional complementation; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Abstract : Synthesis of proteins is performed by the ribosome, a large ribonucleoprotein complex. Apart from the ribosome, numerous protein factors participate in this process. Elongation factor 2 (eEF2) is one of these factors. eEF2 is an essential protein with a mol. READ MORE

  6. 4. The ribosome, stringent factor and the bacterial stringent response

    Author : Rose-Marie Jenvert; Lovisa Holmberg Schiavone; Suparna Sanyal; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; stringent factor; stringent response; tRNA; ribosomal protein L11; pppGpp; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Abstract : The stringent response plays a significant role in the survival of bacteria during different environmental conditions. It is activated by the binding of stringent factor (SF) to stalled ribosomes that have an unacylated tRNA in the ribosomal A-site which leads to the synthesis of (p)ppGpp. READ MORE

  7. 5. The Actin Filament System : Its Involvement in Cell Migration and Neurotransmitter Release

    Author : Anna-Karin Johnsson; Roger Karlsson; Stéphane Gasman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Actin; Profilin; Synaptotagmin; Cell biology; Cellbiologi; Cell Biology; cellbiologi;

    Abstract : The microfilament system consists of actin filaments as the major component and is regulated by a number of actin binding proteins. It is juxtaposed to the plasma membrane where it forms a dense cortical weave from where it pervades into the cell interior. READ MORE