Search for dissertations about: "cellular aging"

Showing result 21 - 25 of 67 swedish dissertations containing the words cellular aging.

  2. 21. Transcriptome studies of cell-fate and aging

    Author : Ola Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Microarray; senescence; apoptosis; aging; expression profiling;

    Abstract : Microarrays enable the researcher to capture the expression levels from most genes in a single experiment. The methodology has opened up a new field with possibilities and challenges. READ MORE

  4. 22. Protein Engineering of Extracellular Superoxide Dismutase : Characterization of Binding to Heparin and Cellular Surfaces

    Author : Ing-Marie Ahl; Lena Tibell; Bengt-Harald Jonsson; Steen Vang Petersen; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : Accumulating evidence indicates that oxygen free radicals are involved in many diseases and pathological conditions, such as aging, inflammation, reperfusion damage of ischemic tissue and various cardiovascular diseases. Extracellular superoxide dismutase (ECSOD) thus plays a major role in the maintenance of cells by providing protection against these toxic substances in the extracellular space. READ MORE

  5. 23. Old-age muscle atrophy : cellular mechanisms and behavioral consequenses

    Author : Mikael Altun; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : With advancing age, humans and rodents alike lose about one third of the skeletal muscle mass. A process referred to as old-age muscle atrophy or sarcopenia. READ MORE

  6. 24. Striatal glutamatergic neurotransmission and plasticity in Parkinson’s disease and aging

    Author : Mona Nouhi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Parkinson's disease (PD) is a devastating neurodegenerative disorder with aging as the main risk factor. PD is characterized by severe movement disturbances but is also associated with non-motor symptoms. READ MORE

  7. 25. Profiling of microglia in inflammation, aging, and the tumor microenvironment

    Author : Lara Friess; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In this thesis I aim to present our ongoing efforts to elucidate activation states and how these are regulated in microglia cells. An extensive body of work is dedicated to understanding how these resident immune cells can acquire certain activation states, as their roles are crucial for a great range of functions in the central nervous system – from homeostasis to pathological occurrences. READ MORE