Search for dissertations about: "cellular deformation"

Showing result 11 - 15 of 23 swedish dissertations containing the words cellular deformation.

  2. 11. RICH-1, a Multifunctional RhoGAP Domain-containing Protein, Involved in Regulation of the Actin Filament System and Membrane-trafficking

    Author : Ninna Richnau; Pontus Aspenström; Carl-Henrik Heldin; Bengt Hallberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Rho GTPase; RhoGAP; actin; BAR domain; membrane-trafficking; formin homology proteins; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The Rho GTPases, which are related to the Ras family of proto-oncogenes, have been found to have important roles in regulating the morphogenic and migratory properties of eukaryotic cells. In addition, these proteins have been shown to regulate aspects of cell signaling, cell growth, cell division and cell survival. READ MORE

  4. 12. Modeling of material behavior in metal forming

    Author : Håkan Hallberg; Hållfasthetslära; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : With an increasing demand to improve efficiency and to cut costs, the industry is constantly seeking to reduce the time and money spent in product development and manufacturing. Use of computer-based simulations has become more or less a standard tool to meet this demand. READ MORE

  5. 13. Clusterin and Megalin in The Spinal Cord

    Author : Grzegorz Wicher; Hakan Aldskogius; Lars Hillered; Anders Lewen; Robin Franklin; Uppsala universitet; []
    Keywords : Neurosciences; nerve degeneration; hypoglossal nerve; chaperone; apolipoprotein; development; transcription factor; astrocyte; glial differentiation; myelin; cell signalling; Neurovetenskap;

    Abstract : Nerve injury induces up-regulation of the chaperone protein clusterin in affected neurons and adjacent astrocytes but the functional significance of this response is unclear. We find that motor neuron survival is significantly greater in clusterin(+/+) compared to (-/-) mice. READ MORE

  6. 14. Image processing methods to study the living hearing organ

    Author : Miriam von Tiedemann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In this thesis we are developing image processing methods allowing one to probe the structure and function of the mammalian hearing organ, an intricate cellular assembly with a highly specialized three-dimensional organization. Confocal as well as electron microscopy was used for image acquisition. READ MORE

  7. 15. Non-canonical ATG8 conjugation in ESCRT-driven membrane remodeling processes

    Author : Anastasia Knyazeva; Yao-Wen Wu; Richard Lundmark; Sascha Martens; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ATG8 conjugation; Endosomal Sorting Complex Required for Transport; membrane remodeling; chemical genetics;

    Abstract : ATG8 family proteins have the unique ability to conjugate to membrane lipids. Initially identified as a hallmark of autophagy, ATG8 lipidation is emerging as an important regulator of a growing list of non-degradative cellular functions. READ MORE