Search for dissertations about: "cellular immunity"

Showing result 6 - 10 of 182 swedish dissertations containing the words cellular immunity.

  1. 6. Activation of the Cellular Immune Response in Drosophila melanogaster Larvae

    Author : Ines Anderl; Dan Hultmark; Paul Badenhorst; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; immunity; blood cells; hematopoiesis; flow cytometry; in vivo imaging; genetic screens; Tl10b; fat body; Toll signaling; molekylärbiologi; Molecular Biology;

    Abstract : During the last 40 years, Drosophila melanogaster has become an invaluable tool in understanding innate immunity. The innate immune system of Drosophila consists of a humoral and a cellular component. While many details are known about the humoral immune system, our knowledge about the cellular immune system is comparatively small. READ MORE

  2. 7. Cellular Immune Responses to Cytomegalovirus

    Author : Anna Karin Lidehäll; Olle Korsgren; Thomas Tötterman; Ineke ten Berge; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; cellular immunology; infection; immune responses; congenital infection; CD4 T cells; CD8 T cells; immunosuppressed; Clinical immunology; Klinisk immunologi;

    Abstract : Cytomegalovirus (CMV) is a widespread infection affecting 50-90% of the human population. A typical silent primary infection is followed by life-long persistence in the host under control by virus-specific CD8 (“killer”) and CD4 (“helper”) T cells. READ MORE

  3. 8. Signaling pathways in the activation and proliferation of Drosophila melanogaster blood cells

    Author : Carl-Johan Zettervall; Marie Meister; Umeå universitet; []
    Keywords : innate immunity; cellular immunity; molecular signaling; molekylärbiologi; Molecular Biology;

    Abstract : The larva of the fruit fly Drosophila melanogaster is an excellent model to study the molecular control of innate cellular immune responses. Cellular responses take place, and can be studied, following infestation of the wasp Leptopilina boulardi. This response includes proliferation and activation (differentiation) of the blood cells (hemocytes). READ MORE

  4. 9. Macrophages in Crohn's Disease: lnnate immune cellular and molecular mechanisms driving intestinal inflammation and fibrosis

    Author : Frida Gorreja; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophages; inflammatory macrophages; tissue-resident macrophages; efferocytosis; innate immunity; myeloid cells; fibroblasts; fibrosis; inflammasomes; Crohn´s disease; inflammatory bowel diseases; digestive diseases; mucosa immunology; intestinal immunity; intestinal inflammation; serum systemic inflammation; microbiota; metabolites;

    Abstract : Macrophages and their interactions with the lamina propria and luminal microenvi-ronment are crucial in the pathogenesis of Crohn´s disease (CD), a chronic inflamma-tory disease with a strong inflammatory innate immune involvement. Therefore, in-terpreting macrophage activity in the intestinal microenvironment may identify treatment targets beneficial for at least a subgroup of patients. READ MORE

  5. 10. Neutrophils versus Pathogenic Fungi : through the magnifying glass of nutritional immunity

    Author : Maria Joanna Niemiec; Constantin F. Urban; Bernhard Hube; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Candida albicans; nutritional immunity; metallome; Zn; Fe;

    Abstract : Neutrophils are among the first white blood cells recruited to the site of infection once microbial pathogens enter the host organism. At site, they perform a well-orchestrated chain of processes that aims to kill the microbial invader. Most prominent, neutrophils engulf microbes to inactivate them intracellularly, a process called phagocytosis. READ MORE